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Sigma-Aldrich

Sulfato de dextrana

low sulfate content, Mr ~40,000

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About This Item

Número CAS:
Número MDL:
Código UNSPSC:
12352201
NACRES:
NA.25

fonte biológica

(Leuconostoc spp)

Nível de qualidade

forma

powder

qualidade

low sulfate content

peso molecular

Mr ~40,000

composição

Sulfur Content, 8-13%

perda

≤10% loss on drying

cor

white to off-white

faixa de pH útil

6.0-8 (10 g/L)

solubilidade

H2O: 100 mg/mL, clear, colorless to faintly greenish-yellow

temperatura de armazenamento

room temp

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Descrição geral

Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran.

Aplicação

Dextran sulfate increases binding of epithelial cells and lymphocytes to extracellular matrix proteins including fibronectin and laminin. In addition, dextran sulfate altered expreβion of cell surface receptors integrins.
Dextran sulfate is routinely used for the selective precipitation of lipoproteins, probe hybridization membrane-immobilized DNA, the release of DNA from DNA-histone complexes, and the inhibition of RNA binding to ribosomes.

Nota de preparo

Sigma dextrans are derived from Leuconostoc mesenteroides.

Outras notas

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

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Sigma-Aldrich

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Dextran Mr ~40,000

Sigma-Aldrich

31389

Dextran

J Ni et al.
Gut, 39(2), 234-241 (1996-08-01)
The effects of dextran sulphate sodium (DSS) on mouse intestinal epithelial cells and intraepithelial lymphocytes were analysed to investigate the mechanism by which DSS induces colitis and tumours in mice. Cytotoxicity of DSS towards intestinal epithelial cells and intestinal intraepithelial
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An important role has emerged for calpain enzymes in regulating inflammation with one isoform, calpain-2, particularly important for macrophage activation. The goal of this study was to determine the therapeutic potential of a synthetic calpain-2 inhibitor, zLLY-CH2F, for colitis and

Artigos

Additional information about FITC-labelled polysaccarides including FITC-Dextran, FITC-DEAE-dextran (FDD), FITC-carboxymethyl-dextran (FCM-Dextran). This page discusses the impact of weight-average molecular weight on the respective molecule dimensions and other physical properties

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