S9876

Sulfathiazole

• Sinônimo(s): 2-Sulfanilamidothiazole, 4-Amino-N-(2-thiazolyl)benzenesulfonamide, N₁-(2-Thiazolyl)sulfanilamide
• Fórmula empírica (Notação de Hill): C₉H₉N₃O₂S₂
• Número CAS: 72-14-0
• Peso molecular: 255.32
• Beilstein: 226178
• Número CE: 200-771-5
• Número MDL: MFCD00005319
• Código UNSPSC: 41116107
• ID de substância PubChem: 329824636
• NACRES: NA.24

Propriedades

• grau: analytical standard
• Nível de qualidade: 100
• Agency: EPA 1694
• forma: powder
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• pf: 200-202 °C (lit.)
• aplicação(ões): clinical testing
• cadeia de caracteres SMILES: Nc1ccc(cc1)S(=O)(=O)Nc2nccs2
• InChI: 1S/C9H9N3O2S2/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9/h1-6H,10H2,(H,11,12)
• chave InChI: JNMRHUJNCSQMMB-UHFFFAOYSA-N

Descrição

Descrição geral

Sulfathiazole is a broad-spectrum antibacterial drug, belonging to the class of sulfonamides, used in veterinary and human medication for the treatment of infections. It is also involved in promoting growth of livestock and fish.

Aplicação

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Sulfathiazole is used as an analytical reference standard for the quantification of the analyte in meat, and honey samples using different chromatography techniques.

Ações bioquímicas/fisiológicas

Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.
Mode of Action: Inhibits folic acid synthesis in prokaryotes.
Anti-microbial Spectrum: Gram positive, Gram negative, Chlamydia
Mode of Resistance: Alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H315 - H319 - H335 - H412
• Declarações de precaução: P261 - P264 - P271 - P273 - P302 + P352 - P305 + P351 + P338
• Classificações de perigo: Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 2
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves