PHR1379

Atropine Sulfate

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinônimo(s): Atropine sulfate salt monohydrate, α-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, Tropine tropate
• Fórmula linear: (C₁₇H₂₃NO₃)₂ · H₂SO₄ · H₂O
• Número CAS: 5908-99-6
• Peso molecular: 694.83
• Beilstein: 6109275
• Número CE: 200-235-0
• Número MDL: MFCD00074815
• Código UNSPSC: 41116107
• ID de substância PubChem: 329823356
• NACRES: NA.24

Propriedades

• grau: certified reference material; pharmaceutical secondary standard
• Nível de qualidade: 300
• Agency: traceable to BP 23; traceable to Ph. Eur. A1400000; traceable to USP 1045009
• família API: atropine
• Certificado de análise (CofA): current certificate can be downloaded
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• pf: 189-192 °C (A) (lit.)
• aplicação(ões): pharmaceutical (small molecule)
• formato: neat
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: O.OS(O)(=O)=O.CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3.CN4[C@H]5CC[C@@H]4C[C@@H](C5)OC(=O)C(CO)c6ccccc6
• InChI: 1S/2C17H23NO3.H2O4S.H2O/c2*1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12;1-5(2,3)4;/h2*2-6,13-16,19H,7-11H2,1H3;(H2,1,2,3,4);1H2/t2*13-,14+,15+,16?;;
• chave InChI: JPKKQJKQTPNWTR-CHYDPLAESA-N
• Informações sobre genes: human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131)

Descrição

Descrição geral

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Atropine Sulfate is an alkaloid extracted from belladonna herb. It is a cholinergic drug, administered as an anti-arrhythmic medicine.

Aplicação

Atropine Sulfate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by electrophoresis and chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Ações bioquímicas/fisiológicas

Competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAC4087 in the slot below. This is an example certificate only and may not be the lot that you receive.

Informações de segurança

• Pictogramas: GHS06
• Palavra indicadora: Danger
• Frases de perigo: H300 + H330
• Declarações de precaução: P260 - P264 - P271 - P284 - P304 + P340 + P310 - P403 + P233
• Classificações de perigo: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Código de classe de armazenamento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable