1045009

Atropine sulfate

United States Pharmacopeia (USP) Reference Standard

• Sinônimo(s): Atropine sulfate salt monohydrate, α-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, Tropine tropate
• Fórmula linear: (C₁₇H₂₃NO₃)₂ · H₂SO₄ · H₂O
• Número CAS: 5908-99-6
• Peso molecular: 694.83
• Beilstein: 6109275
• Número MDL: MFCD00074815
• Código UNSPSC: 41116107
• ID de substância PubChem: 329749082
• NACRES: NA.24

Propriedades

• grau: pharmaceutical primary standard
• família API: atropine
• fabricante/nome comercial: USP
• pf: 189-192 °C (A) (lit.)
• aplicação(ões): pharmaceutical (small molecule)
• Formato: neat
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: O.OS(O)(=O)=O.CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3.CN4[C@H]5CC[C@@H]4C[C@@H](C5)OC(=O)C(CO)c6ccccc6
• InChI: 1S/2C17H23NO3.H2O4S.H2O/c2*1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12;1-5(2,3)4;/h2*2-6,13-16,19H,7-11H2,1H3;(H2,1,2,3,4);1H2/t2*13-,14+,15+,16?;;
• chave InChI: JPKKQJKQTPNWTR-CHYDPLAESA-N
• Informações sobre genes: human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131)

Descrição

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Atropine sulfate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Atropine Sulfate Injection
• Atropine Sulfate Ophthalmic Solution
• Atropine Sulfate Ophthalmic Ointment
• Diphenoxylate Hydrochloride and Atropine Sulfate Tablets
• Diphenoxylate Hydrochloride and Atropine Sulfate Oral Solution
• Atropine

Ações bioquímicas/fisiológicas

Competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors.

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Informações de segurança

• Pictogramas: GHS06
• Palavra indicadora: Danger
• Frases de perigo: H300 + H330
• Declarações de precaução: P301 + P310 + P330 - P304 + P340 + P310
• Classificações de perigo: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Código de classe de armazenamento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de risco de água (WGK): WGK 3