PHR1074

Oxybenzone

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinônimo(s): 2-Hydroxy-4-methoxybenzophenone, Oxybenzone
• Fórmula linear: HOC₆H₃(OCH₃)COC₆H₅
• Número CAS: 131-57-7
• Peso molecular: 228.24
• Beilstein: 1913145
• Número CE: 205-031-5
• Número MDL: MFCD00008387
• Código UNSPSC: 41116107
• eCl@ss: 39023842
• ID de substância PubChem: 329823097
• NACRES: NA.24

Propriedades

• grau: certified reference material; pharmaceutical secondary standard
• Nível de qualidade: 300
• Agency: traceable to USP 1485001
• família API: oxybenzone
• Certificado de análise (CofA): current certificate can be downloaded
• técnica(s): HPLC: suitable; gas chromatography (GC): suitable
• pb: 150-160 °C/5 mmHg (lit.)
• pf: 62-64 °C (lit.)
• aplicação(ões): environmental; pharmaceutical (small molecule)
• formato: neat
• temperatura de armazenamento: 2-30°C
• cadeia de caracteres SMILES: COc1ccc(c(O)c1)C(=O)c2ccccc2
• InChI: 1S/C14H12O3/c1-17-11-7-8-12(13(15)9-11)14(16)10-5-3-2-4-6-10/h2-9,15H,1H3
• chave InChI: DXGLGDHPHMLXJC-UHFFFAOYSA-N

Descrição

Descrição geral

Oxybenzone, also known as benzophenone-3, belongs to the class of aromatic organic UV filters. It is categorized as an endocrine disruptor chemical (EDC) as it can interfere with the endocrine system. It exhibits estrogenic activity through its interaction with the estrogen receptors alpha (ERα) and beta (ERβ). It is a lipophilic, broad-spectrum sunscreen agent which absorbs ultraviolet B (290−320 nm), some ultraviolet A (320−360 nm), and some ultraviolet C (250−290 nm) radiations. It is widely used as an active compound in commercial sunscreens, creams, lotions, lipsticks, perfumes, shower bath, hair sprays, shampoos, and transparent packing material of products.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Aplicação

Oxybenzone may be used as a pharmaceutical reference standard in the determination of the analyte in pharmaceutical formulations by spectrophotometric and chromatographic techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Nota de análise

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Outras notas

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota de rodapé

To see an example of a Certificate of Analysis for this material enter LRAB3268 in the slot below. This is an example certificate only and may not be the lot that you receive.

Produtos recomendados

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informações de segurança

• Pictogramas: GHS09
• Palavra indicadora: Warning
• Frases de perigo: H410
• Declarações de precaução: P273 - P391 - P501
• Classificações de perigo: Aquatic Acute 1 - Aquatic Chronic 2
• Código de classe de armazenamento: 13 - Non Combustible Solids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): 212.0 °F - closed cup
• Ponto de fulgor (°C): 100 °C - closed cup