M2772

Menthol

99%

• Sinônimo(s): 2-Isopropyl-5-methylcyclohexanol, Hexahydrothymol
• Fórmula empírica (Notação de Hill): C₁₀H₂₀O
• Número CAS: 89-78-1
• Peso molecular: 156.27
• Beilstein: 3194263
• Número CE: 201-939-0
• Número MDL: MFCD00001484
• Código UNSPSC: 12352212
• ID de substância PubChem: 24896764
• NACRES: NA.25

Propriedades

• pressão de vapor: 0.8 mmHg ( 20 °C)
• Nível de qualidade: 200
• Ensaio: 99%
• p.e.: 216 °C (lit.)
• pf: 34-36 °C (lit.)
• densidade: 0.89 g/mL at 25 °C (lit.)
• aplicação(ões): metabolomics; vitamins, nutraceuticals, and natural products
• cadeia de caracteres SMILES: CC(C)C1CCC(C)CC1O
• InChI: 1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3
• chave InChI: NOOLISFMXDJSKH-UHFFFAOYSA-N
• Informações sobre genes: human ... TRPA1(8989) , TRPM8(79054)

Descrição

Descrição geral

Menthol (C₁₀H₂₀O) is a terpenoid compound. It is extracted from the plants belonging to Mentha genus in the Lamiaceae family.

Menthol is a cyclic monoterpene alcohol, which is extracted from essential oils of Mentha canadensis and Mentha x piperita. It possesses antimicrobial, anticancer and anti-inflammatory properties. Menthol acts as a transient receptor potential cation channel (TRPM8) agonist. It also exhibits analgesic, antipruritic, anesthetic and cooling effects.

Aplicação

Menthol has been used:

• to test its antifungal susceptibility
• to determine its efficacy as an anesthetic in fish
• to activate transient receptor potential cation channel (TRPM8)
• as an odorant for measuring sniffing dynamics

Ações bioquímicas/fisiológicas

Menthol exhibits antifungal action on the membrane permeability and the cell wall consistency, this might leads to cell death or inhibition of the C. albicans filamentation. Therefore, it can be used as a potential therapeutic agent for candidiasis. In addition to antifungal activity, menthol also exhibits anesthetic, antispasmodic, anti-ulcer and antiviral properties. It is considered as a safe compound for animal life. Therefore, Menthol is widely used in pharmaceuticals, cosmetics and food industries.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H315,H319
• Declarações de precaução: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Classificações de perigo: Eye Irrit. 2 - Skin Irrit. 2
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 204.8 °F
• Ponto de fulgor (°C): 96 °C
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves