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C7129

Sigma-Aldrich

Ácido cítrico

reagent grade, ≥98% (GC/titration)

Sinônimo(s):

2-hydroxy-1,2,3-propanetricarboxylic acid monohydrate

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About This Item

Fórmula linear:
HOC(COOH)(CH2COOH)2 · H2O
Número CAS:
5949-29-1
Peso molecular:
210.14
Beilstein:
4018641
Número CE:
201-069-1
Número MDL:
MFCD00149972
Código UNSPSC:
12352100
ID de substância PubChem:
24892935
NACRES:
NA.21

grau

reagent grade

Ensaio

≥98% (GC/titration)

forma

powder

pKa 

(1) 3.13, (2) 4.76, (3) 6.4

solubilidade

H2O: 100 mg/mL, clear, colorless (Turbidity)

cadeia de caracteres SMILES

OC(CC(O)(C(O)=O)CC(O)=O)=O.O

InChI

1S/C6H8O7.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);1H2

chave InChI

YASYEJJMZJALEJ-UHFFFAOYSA-N

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Descrição geral

Citric acid monohydrate(CAM) is an organic acid. It can be produced by crystallization from mother liquor of citric acid solution at 20-25°C during citric acid synthesis. Its molar enthalpy of solution in water has been reported to be ΔsolHm (298.15K, m = 0.0203molkg-1) = (29061±123)Jmol-1. An investigation of its crystal growth kinetics indicates that growth is linearly dependent on size.

Aplicação

Citric acid monohydrate may be used:
  • To prepare citric acid solution employed in the acetone method of 68Ga pre-purification and radiolabeling technique.
  • To prepare Tris-citrate buffer employed for the electrophoresis of bacterial enzymes.
  • To improve the release of diltiazem hydrochloride from melt extruded matrix tablets.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H319,H335

Classificações de perigo

Eye Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

345.0 °F - closed cup

Ponto de fulgor (°C)

173.9 °C - closed cup

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análise (COA)

Lot/Batch Number
SLCL9406
SLCL5922
SLCL0802
SLCL0759
SLCK9585

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Sigma-Aldrich

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Ácido cítrico

Citrato de sódio tribásico ≥98%

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Potassium citrate tribasic monohydrate ≥98% (GC/titration)

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Size dependency of citric acid monohydrate growth kinetics.
Bravi M and Mazzarotta B.
Chemical Engineering Journal, 70(3), 203-207 (1998)
Methods of multilocus enzyme electrophoresis for bacterial population genetics and systematics.
R K Selander et al.
Applied and environmental microbiology, 51(5), 873-884 (1986-05-01)
Michael K Schultz et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 76, 46-54 (2012-10-03)
A new NaCl based method for preparation of gallium-68 labeled radiopharmaceuticals has been adapted for use with an automated gallium-68 generator system. The method was evaluated based on 56 preparations of [(68)Ga]DOTATOC and compared to a similar acetone-based approach. Advantages
New perspectives for citric acid production and application.
Soccol CR, et al.
Food Technology and Biotechnology, 44(2), 141-149 (2006)
Sandra U Schilling et al.
International journal of pharmaceutics, 361(1-2), 158-168 (2008-06-28)
Incomplete drug release and particle size-dependent dissolution performance can compromise the quality of controlled release matrix systems. The objective of the current study was to investigate the ability of citric acid monohydrate (CA MH) to enhance the release of diltiazem
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