C0166000

Calcifediol

European Pharmacopoeia (EP) Reference Standard

• Sinônimo(s): 25-Hydroxyvitamin D₃ monohydrate, 25-Hydroxycholecalciferol
• Fórmula empírica (Notação de Hill): C₂₇H₄₄O₂ · H₂O
• Número CAS: 63283-36-3
• Peso molecular: 418.65
• Beilstein: 4270041
• Número MDL: MFCD00867077
• Código UNSPSC: 41116107
• ID de substância PubChem: 329774765
• NACRES: NA.24

Propriedades

• fonte biológica: sheep wool (grease)
• grau: pharmaceutical primary standard
• Agency: EP
• família API: calcifediol
• forma: solid
• fabricante/nome comercial: EDQM
• técnica(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• aplicação(ões): pharmaceutical (small molecule)
• formato: neat
• cadeia de caracteres SMILES: [H][C@@]1(CC[C@@]2([H])C(\CCC[C@]12C)=C\C=C3\C[C@@H](O)CCC3=C)[C@H](C)CCCC(C)(C)O
• InChI: 1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1
• chave InChI: JWUBBDSIWDLEOM-DTOXIADCSA-N
• Informações sobre genes: human ... VDR(7421)

Descrição

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.Calcifediol is a biologically active metabolite of vitamin D. It is more hydrophilic and better absorbed in the intestine when compared to ergocalciferol or cholecalciferol due to the high affinity for the vitamin-D-binding protein. The drug is known to treat diseases associated with decreased intestinal absorption and obesity.

Aplicação

Calcifediol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

Informações de segurança

• Pictogramas: GHS06,GHS08
• Palavra indicadora: Danger
• Frases de perigo: H301 + H311,H330,H372
• Declarações de precaução: P260 - P264 - P280 - P302 + P352 + P312 - P304 + P340 + P310 - P314
• Classificações de perigo: Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - STOT RE 1 Oral
• Código de classe de armazenamento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable