437573

N,N-Dimetilformamida

ACS reagent, ≥99.8%

• Sinônimo(s): DMF, NSC 5356
• Fórmula linear: HCON(CH₃)₂
• Número CAS: 68-12-2
• Peso molecular: 73.09
• Beilstein: 605365
• Número CE: 200-679-5
• Número MDL: MFCD00003284
• Código UNSPSC: 12352111
• ID de substância PubChem: 24867382

Propriedades

• grau: ACS reagent
• Nível de qualidade: 200
• densidade de vapor: 2.5 (vs air)
• pressão de vapor: 2.7 mmHg ( 20 °C)
• Ensaio: ≥99.8%
• forma: liquid
• temperatura de autoignição: 833 °F
• Lim. expl.: 15.2 %
• técnica(s): electrophoresis: suitable
• Impurezas: ≤0.0005 meq/g Titr. acid; ≤0.003 meq/g Titr. base; ≤0.15% water
• resíduo de evaporação: ≤0.005%
• cor: APHA: ≤15
• índice de refração: n20/D 1.430 (lit.)
• pH: 6.7
• pb: 153 °C (lit.)
• pf: −61 °C (lit.)
• solubilidade: water: miscible
• densidade: 0.944 g/mL (lit.)
• cadeia de caracteres SMILES: [H]C(=O)N(C)C
• InChI: 1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3
• chave InChI: ZMXDDKWLCZADIW-UHFFFAOYSA-N

Descrição

Descrição geral

N,N-Dimethylformamide (DMF) is a polar organic solvent with a wide range of industrial applications. It is a precursor for numerous reactions such as formylation, aminocarbonylation, amination, amidation and cyanation. Along with phosphorus oxychloride, it forms Vilsmeier reagent used in the formylation of reactive aromatic and heteroaromatic substrates. Dielectric relaxation experiments on DMF have been conducted between 238.15K and 338.15K. The thermophysical properties of the molecular interactions between DMF and the ionic liquids, ammonium salts and imidazolium salts have been studied. The characteristics of solute-solvent interactions between ammonium nitrate and DMF have been investigated.

Aplicação

N,N-Dimethylformamide (DMF) may be used in the following processes:

• As a solvent synthesis of gold nanoparticles.
• As a solvent in capillary electrophoresis.
• Regioselective synthesis of N,N-dimethylaminopyridzines by reacting with choropyridazines.
• Synthesis of urea-N,N-dimethylformamide, a 3:1 solvate with urea.

Solvente de muitos compostos orgânicos hidrofóbicos.

Informações de segurança

• Pictogramas: GHS02,GHS08,GHS07
• Palavra indicadora: Danger
• Frases de perigo: H226,H312 + H332,H319,H360D
• Declarações de precaução: P210 - P280 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313
• Classificações de perigo: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B
• Código de classe de armazenamento: 3 - Flammable liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): 135.5 °F - closed cup
• Ponto de fulgor (°C): 57.5 °C - closed cup
• Equipamento de proteção individual: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter