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Key Documents

33626

Sigma-Aldrich

Sulfanilamide

puriss. p.a., ≥98% (calc. to the dried substance)

Sinônimo(s):

p-Aminobenzenesulfonamide

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About This Item

Fórmula linear:
H2NC6H4SO2NH2
Número CAS:
Peso molecular:
172.20
Beilstein:
511852
Número CE:
Número MDL:
Código UNSPSC:
12352100
eCl@ss:
39093202
ID de substância PubChem:
NACRES:
NA.21

grau

puriss. p.a.

Nível de qualidade

Ensaio

≥98% (calc. to the dried substance)

forma

solid

Impurezas

≤0.002% heavy metals (as Pb)

resíduo de ignição

≤0.1% (as SO4)

perda

≤0.5% loss on drying, 105 °C

cor

white to faint beige

pf

163-166 °C
164-166 °C (lit.)

traços de ânion

chloride (Cl-): ≤100 mg/kg
sulfate (SO42-): ≤200 mg/kg

espectro de atividade do antibiótico

Gram-negative bacteria
Gram-positive bacteria

Modo de ação

DNA synthesis | interferes
enzyme | inhibits

cadeia de caracteres SMILES

Nc1ccc(cc1)S(N)(=O)=O

InChI

1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)

chave InChI

FDDDEECHVMSUSB-UHFFFAOYSA-N

Informações sobre genes

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Descrição geral

Chemical structure: sulfonamide
Sulfanilamide (p-Aminobenzenesulfonamide) is a para-amino substituted benzenesulfonamide. Its ortho-mono and diiodo derivatives have been synthesized.

Aplicação

  • Study of new azo-azomethine derivatives of sulfanilamide: synthesis, characterization, spectroscopic, antimicrobial, antioxidant and anticancer activity: This study explores new derivatives of sulfanilamide synthesized through diazonium salt reactions and coupling with 2-hydroxy-3-methoxybenzaldehyde, providing insights into their potential antimicrobial, antioxidant, and anticancer activities (HS Al-Atbi, IJ Al-Assadi, et al., 2020).

Embalagem

33626-100G; 33626-6X100G

Outras notas

Keep container tightly closed in a dry and well-ventilated place.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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A series of compounds incorporating regioisomeric phenylethynylbenzenesulfonamide moieties has been investigated for the inhibition of four human carbonic anhydrase (hCA, EC 4.2.1.1) isoforms, hCA I, II, IX and XII. Inhibition between the low nanomolar to the milliomolar range has been

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