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Key Documents

FCABS352A4

Sigma-Aldrich

Milli-Mark® Anti-Nanog-Alexa Fluor 488 Antibody, NT

Milli-Mark®, from rabbit

Sinônimo(s):

Homeobox transcription factor Nanog, Nanog homeobox

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About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

conjugado

ALEXA FLUOR 488

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

reatividade de espécies

human

reatividade da espécie (prevista por homologia)

mouse (based on 100% sequence homology), rat (based on 100% sequence homology)

fabricante/nome comercial

Milli-Mark®

técnica(s)

flow cytometry: suitable

Isotipo

IgG

nº de adesão NCBI

nº de adesão UniProt

Condições de expedição

wet ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

human ... NANOG(79923)

Descrição geral

NANOG is a gene expressed in embryonic stem cells (ESCs) and is thought to be a key factor in maintaining pluripotency. NANOG thought to function in concert with other factors such as POU5F1 and SOX2 to establish ESC identity. These cells offer an important area of study because of their ability to maintain pluripotency, i.e., these cells have the ability to become virtually any cell of any of the three germ layers (endoderm, ectoderm, mesoderm).
NANOG may be useful in the immunohistochemical diagnosis of tumors. NANOG is expressed in germ cells of the fetus and in some germ cell tumors of the gonads and central nervous system (CNS).

Especificidade

Antibody recognizes NANOG.

Imunogênio

Epitope: N-terminus
Linear peptide from mouse Nanog.

Aplicação

Milli-Mark Anti-Nanog-Alexa Fluor 488 Antibody, N-terminus is an antibody against Nanog-Alexa Fluor 488 for use in FC.
Research Category
Stem Cell Research
Research Sub Category
Pluripotent & Early Differentiation

Qualidade

Evaluated by flow cytometry using 2102 Ep cells

Descrição-alvo

34 kDa Calculated

forma física

Antigen Affinity Purified
Purified rabbit polyclonal IgG conjugated to Alexa Fluor 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA

Armazenamento e estabilidade

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Nota de análise

Control
2102 Ep cells

Informações legais

ALEXA FLUOR is a trademark of Life Technologies
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

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Stem cell research, 37, 101436-101436 (2019-04-23)
Niemann-Pick disease type B (NPB) is a rare autosomal recessive lysosomal storage disease caused by mutations in the SMPD1 gene, which encodes for acid sphingomyelinase. A human induced pluripotent stem cell (iPSC) line was generated from dermal fibroblasts of a
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Stem cell research, 54, 102400-102400 (2021-05-30)
NGLY1 deficiency is a rare disorder caused by mutations in the NGLY1 gene which codes for the highly conserved N-glycanase1 (NGLY1). This enzyme functions in cytosolic deglycosylation of N- linked glycoproteins. An induced pluripotent stem cell (iPSC) line was generated
Wei Huang et al.
Stem cell research, 37, 101427-101427 (2019-04-02)
Mucopolysaccharidosis type III B (MPS IIIB) is a lysosomal storage disorder caused by mutations in the NAGLU gene encoding N-acetylglucosaminidase. Here, we report the generation of a human induced pluripotent stem cell (iPSC) line from dermal fibroblasts of a MPS
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Mucopolysaccharidosis Type II (MPS II), also known as Hunter syndrome, is a rare X-linked genetic disease caused by mutations in the IDS gene encoding iduronate 2-sulfatase (I2S). This is a multisystem disorder with significant variation in symptoms. Here, we document

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