Pular para o conteúdo
Merck
Todas as fotos(4)

Documentos Principais

AB4336

Sigma-Aldrich

Anti-SCA-1 Antibody

from rabbit, purified by affinity chromatography

Sinônimo(s):

Lymphocyte antigen 6A-2/6E-1, Ly-6A.2/Ly-6E.1, T-cell-activating protein, Stem cell antigen 1

Faça loginpara ver os preços organizacionais e de contrato


About This Item

Código UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

fonte biológica

rabbit

Nível de qualidade

forma do anticorpo

affinity isolated antibody

tipo de produto de anticorpo

primary antibodies

clone

polyclonal

purificado por

affinity chromatography

reatividade de espécies

rat, mouse

técnica(s)

immunocytochemistry: suitable
western blot: suitable

nº de adesão NCBI

nº de adesão UniProt

Condições de expedição

wet ice

modificação pós-traducional do alvo

unmodified

Informações sobre genes

mouse ... Ly6A(110454)

Descrição geral

Stem cell antigen 1 (SCA-1) is a membrane protein belonging to the Ly-6 family of proteins and contains a single UPAR/Ly6 domain. SCA-1 is involved in the activation of T-cells and is thought to have a critical role in the differentiation, proliferation, and survival of a variety of stem cells. Recent studies have indicated SCA-1 to be an ideal marker for the isolation and purification of stem cells for research and further characterization. It is expressed by both progenitor and stem cells from several tissue types including; cardiac, hematopoietic, mammary, muscle, skin and testis.

Especificidade

No Homology to human was found.
This antibody recognizes SCA-1 at the UPAR/Ly6 domain.

Imunogênio

Epitope: UPAR/Ly6 domain
KLH-conjugated linear peptide corresponding to mouse SCA-1 at the UPAR/Ly6 domain.

Aplicação

Anti-SCA-1 Antibody is an antibody against SCA-1 for use in WB & IC.
Immunocytochemistry Analysis: A 1:500 dilution from a previous lot detected SCA-1 in rat mesenchymal stem cells.
Research Category
Stem Cell Research
Research Sub Category
Hematopoietic Stem Cells

Qualidade

Evaluated by Western Blot in mouse lung tissue lysate.

Western Blot Analysis: 0.1 µg/mL of this antibody detected SCA-1 in 10 µg of mouse lung tissue lysate.

Descrição-alvo

~14 kDa observed

forma física

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.

Armazenamento e estabilidade

Stable for 1 year at 2-8°C from date of receipt.

Nota de análise

Control
Mouse lung tissue lysate

Outras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Não está encontrando o produto certo?  

Experimente o nosso Ferramenta de seleção de produtos.

Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Santosh K Yadav et al.
Cell death & disease, 11(3), 186-186 (2020-03-15)
Providing a conducive microenvironment is critical to increase survival of transplanted stem cells in regenerative therapy. Hyperglycemia promotes stem cell death impairing cardiac regeneration in the diabetic heart. Understanding the molecular mechanisms of high glucose-induced stem cell death is important
Mehmet H Kural et al.
Cell transplantation, 27(9), 1375-1389 (2018-08-11)
Invasive coronary interventions can fail due to intimal hyperplasia and restenosis. Endothelial cell (EC) seeding to the vessel lumen, accelerating re-endothelialization, or local release of mTOR pathway inhibitors have helped reduce intimal hyperplasia after vessel injury. While animal models are
He Wang et al.
Bioactive materials, 16, 433-450 (2022-04-14)
Small-diameter vascular grafts fabricated from synthetic biodegradable polymers exhibit beneficial mechanical properties but often face poor regenerative potential. Different tissue engineering approaches have been employed to improve tissue regeneration in vascular grafts, but there remains a requirement for a new
Eimear Kennedy et al.
Vascular cell, 6(1), 6-6 (2014-03-19)
The A10 and A7r5 cell lines derived from the thoracic aorta of embryonic rat are widely used as models of non-differentiated, neonatal and neointimal vascular smooth muscle cells in culture. The recent discovery of resident multipotent vascular stem cells within

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica