3741

Hemin Chloride

Iron-containing compound of porcine origin that can induce hydrogen peroxide-dependent lipid peroxidation. Reported to increase the number and size of myotubes and the frequency of myotube contractions.

• Sinônimo(s): Hemin Chloride
• Número CAS: 16009-13-5
• Número MDL: MFCD00010726
• Código UNSPSC: 12352202
• NACRES: NA.21

Propriedades

• Nível de qualidade: 100
• descrição: Merck USA index - 14, 4644
• Formulário: solid
• fabricante/nome comercial: Calbiochem^®
• condição de armazenamento: OK to freeze; protect from light
• cor: dark purple
• solubilidade: 0.1-1.0 M NaOH: soluble; 1 N NH₄OH: soluble
• Condições de expedição: ambient
• temperatura de armazenamento: 15-25°C
• InChI: 1S/C34H34N4O4.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);/q;+3/p-2
• chave InChI: GGIDWJQWCUJYRY-UHFFFAOYSA-L

Descrição

Descrição geral

Iron containing compound of porcine origin that can induce H₂O₂-dependent lipid peroxidation. Reported to increase the number and size of myotubes and the frequency of myotube contractions. Induces heme-oxygenase-1 activity and reduces renal injury induced by mercuric compounds.

Iron-containing compound of porcine origin that can induce hydrogen peroxide-dependent lipid peroxidation. Reported to increase the number and size of myotubes and the frequency of myotube contractions.

Aplicação

• Porphyrins ameliorate spinocerebellar ataxia type 36 GGCCTG repeat expansion-mediated cytotoxicity: Discusses the therapeutic potentials of hemin chloride in neurological disorders, highlighting its role in mitigating cytotoxic effects associated with genetic mutations, significant for advancing neurodegenerative disease treatments (Hirayanagi K et al., 2021).


• Indirect Quantification of Glyphosate by SERS Using an Incubation Process With Hemin as the Reporter Molecule: A Contribution to Signal Amplification Mechanism: Demonstrates the application of hemin chloride in enhancing signal detection in spectroscopic analysis, important for improving analytical methods in environmental and food sciences (López-Castaños KA et al., 2020).

Advertência

Toxicity: Standard Handling (A)

Reconstituição

Unstable in solution; reconstitute just prior to use.

Nota de análise

homogeneous by TLC

Outras notas

Yonega, R., et al. 2000. Toxicol. Lett.116, 223.
Funanage, V.L., et al. 1989. J. Cell. Physiol.141, 591.

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable