2011

Bilirubin

solid, bile pigment, Calbiochem^®

• Sinônimo(s): Bilirubin
• Fórmula empírica (Notação de Hill): C₃₃H₃₆N₄O₆
• Número CAS: 635-65-4
• Peso molecular: 584.66
• Número MDL: MFCD00005499
• Código UNSPSC: 12352200
• NACRES: NA.77

Propriedades

• product name: Bilirubin, Principal pigment of bile and one of the major end products of hemoglobin decomposition.
• Nível de qualidade: 100
• forma: solid
• fabricante/nome comercial: Calbiochem^®
• condição de armazenamento: OK to freeze; protect from light
• cor: red-brown
• solubilidade: chloroform: 1 mg/mL; alkaline solution: soluble
• Condições de expedição: ambient
• temperatura de armazenamento: 10-30°C
• InChI: 1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-
• chave InChI: BPYKTIZUTYGOLE-IFADSCNNSA-N

Descrição

Descrição geral

Bilirubin is an orange-yellow bile pigment and one of the major end products of hemoglobin decomposition. It contains conjugated double bonds and reactive hydrogen atoms. In adults, the upper limit of the normal range of bilirubin is >1mg/dL. Serum levels of bilirubin in healthy newborns are less than 15 mg/dl. This product corresponds to the unconjugated form.

Ações bioquímicas/fisiológicas

Bilirubin is reported to cross the blood-brain barrier and exert significant antioxidant effects in the brain. This pigment aids in coloration in the various forms of jaundice. Bilirubin levels act as biomarkers in liver and blood disorders. Unconjugated form of bilirubin at lower levels serves as a physiological antioxidant. However, increased concentration of bilirubin is toxic and leads to neonatal hyperbilirubinemia in neonates.

Reconstituição

Unstable in basic solutions; reconstitute just prior to use.

Outras notas

Extinction coefficient (454 nm, CHCl₃):59,100-62,300 M^-1cm^-1.
Cell permeable: no
Reversible: no
Product does not compete with ATP.
Primary Target

Informações legais

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable