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N-008

Supelco

S(−)-Nicotine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Sinônimo(s):

(−)-Nicotine solution

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About This Item

Fórmula empírica (Notação de Hill):
C10H14N2
Número CAS:
54-11-5
Peso molecular:
162.23
Beilstein:
5733110
Número MDL:
MFCD00006369
Código UNSPSC:
41116107
ID de substância PubChem:
329818397
NACRES:
NA.24

grau

certified reference material

Formulário

liquid

Características

Snap-N-Spike®/Snap-N-Shoot®

embalagem

ampule of 1 mL

fabricante/nome comercial

Cerilliant®

concentração

1.0 mg/mL in methanol

técnica(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

aplicação(ões)

forensics and toxicology

Formato

single component solution

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

CN1CCC[C@H]1c2cccnc2

InChI

1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1

chave InChI

SNICXCGAKADSCV-JTQLQIEISA-N

Informações sobre genes

human ... CHRNA4(1137) , CHRNB2(1141)

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Categorias relacionadas

Descrição geral

A Certified Spiking Solution® applicable for use in LC/MS or GC/MS applications such as nicotine testing, forensic analysis or clinical and diagnostic testing. Nicotine is a highly additive tobacco alkaloid associated with numerous health risks such as heart health, mental health and cancer.

Informações legais

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órgãos-alvo

Eyes,Central nervous system

Código de classe de armazenamento

3 - Flammable liquids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

49.5 °F - closed cup

Ponto de fulgor (°C)

9.7 °C - closed cup

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Certificados de análise (COA)

Lot/Batch Number

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Manoranjan S D'Souza et al.
Cold Spring Harbor perspectives in medicine, 3(6), doi:10-doi:10 (2013-06-05)
Nicotine plays an important role in the initiation and maintenance of tobacco smoking. Importantly, chronic nicotine exposure alters the function of brain reward systems, resulting in the development of a nicotine-dependent state. This nicotine-dependent state is associated with aversive affective
Christie D Fowler et al.
Neuropharmacology, 76 Pt B, 533-544 (2013-09-24)
Nicotine stimulates brain reward circuitries, most prominently the mesocorticolimbic dopamine system, and this action plays a critical in establishing and maintaining the tobacco smoking habit. Compounds that attenuate nicotine reward are considered promising therapeutic candidates for tobacco dependence, but many
Marina R Picciotto et al.
Neuropharmacology, 76 Pt B, 545-553 (2013-05-02)
Tobacco smoking in humans is one of the most persistent and widespread addictions and is driven by nicotine in tobacco smoke. Over the last several decades, understanding of the molecular and cellular basis for nicotine addiction has increased tremendously as
Lindsay F Stead et al.
The Cochrane database of systematic reviews, 11, CD000146-CD000146 (2012-11-16)
The aim of nicotine replacement therapy (NRT) is to temporarily replace much of the nicotine from cigarettes to reduce motivation to smoke and nicotine withdrawal symptoms, thus easing the transition from cigarette smoking to complete abstinence. The aims of this
Neal L Benowitz et al.
Tobacco control, 22 Suppl 1, i14-i17 (2013-04-23)
Nicotine is highly addictive and is primarily responsible for the maintenance of cigarette smoking. In 1994, Benowitz and Henningfield proposed the idea of federal regulation of the nicotine content of cigarettes such that the nicotine content of cigarettes would be
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