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860547P

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C18 Glucosyl(β) Ceramide (d18:1/18:0)

Avanti Research™ - A Croda Brand

Sinônimo(s):

D-glucosyl-β-1,1′-N-stearoyl-D-erythro-sphingosine

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About This Item

Fórmula empírica (Notação de Hill):
C42H81NO8
Número CAS:
95119-86-1
Peso molecular:
728.09
Código UNSPSC:
12352211
NACRES:
NA.25

Formulário

powder

embalagem

pkg of 1 × 100 mg (860547P-100mg)
pkg of 1 × 25 mg (860547P-25mg)
pkg of 1 × 5 mg (860547P-5mg)

fabricante/nome comercial

Avanti Research™ - A Croda Brand

tipo de lipídio

sphingolipids

Condições de expedição

dry ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](O)[C@@H]([C@H]1CO)O

InChI

1S/C42H81NO8/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-38(46)43-35(34-50-42-41(49)40(48)39(47)37(33-44)51-42)36(45)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h29,31,35-37,39-42,44-45,47-49H,3-28,30,32-34H2,1-2H3,(H,43,46)/b31-29+/t35-,36+,37?,39+,40?,41?,42+/m0/s1

chave InChI

YMYQEDCYNANIPI-KNSMPFANSA-N

Categorias relacionadas

Aplicação

C18 Glucosyl(β) Ceramide (d18:1/18:0) or D-glucosyl-β-1,1′-N-stearoyl-D-erythro-sphingosine has been used:
  • as a lipid standard for its quantification using differential ion mobility spectrometry (DMS) coupled with liquid chromatography in electrospray ionization tandem mass spectrometry (LC-ESI-DMS-MS/MS) in human plasma
  • in the preparation of lipid dispersions
  • used in an assay to monitor the turnover of glucosylceramide in glucocerebrosidase (GBA1) cell free system

Embalagem

5 mL Amber Glass Screw Cap Vial (860547P-100mg)
5 mL Amber Glass Screw Cap Vial (860547P-25mg)
5 mL Amber Glass Screw Cap Vial (860547P-5mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de classe de armazenamento

11 - Combustible Solids

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Jong Hoon Won et al.
Neuroscience, 427, 1-15 (2019-11-26)
Neurotransmitter release is mediated by ceramide, which is generated by sphingomyelin hydrolysis. In the present study, we examined whether synaptosomal-associated protein 25 (SNAP-25) is involved in ceramide production and exocytosis. Neutral sphingomyelinase 2 (nSMase2) was partially purified from bovine brain
Hongbin Xu et al.
Journal of lipid research, 60(1), 200-211 (2018-11-11)
Cerebrosides, including glucosylceramides (GlcCers) and galactosylceramides (GalCers), are important membrane components of animal cells with deficiencies resulting in devastating lysosomal storage disorders. Their quantification is essential for disease diagnosis and a better understanding of disease mechanisms. The simultaneous quantification of
Zdenek Berger et al.
PloS one, 10(3), e0119141-e0119141 (2015-03-13)
Mutations in glucocerebrosidase (GBA1) cause Gaucher disease and also represent a common risk factor for Parkinson's disease and Dementia with Lewy bodies. Recently, new tool molecules were described which can increase turnover of an artificial substrate 4MUG when incubated with
Victoria Schiffer et al.
PloS one, 15(1), e0227077-e0227077 (2020-01-14)
Gaucher disease is caused by a deficiency in glucocerebrosidase that can result in non-neuronal as well as neuronal symptoms. Common visceral symptoms are an increased organ size, specifically of the spleen, and glucosylceramide as well as glucosylsphingosine substrate accumulations as

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