850469C

18:0-20:4 PC

1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine, chloroform

• Sinônimo(s): 1-octadecanoyl-2-arachidonyl-sn-glycero-3-phosphocholine; SAPC; PC(18:0/20:4(5Z,8Z,11Z,14Z))
• Fórmula empírica (Notação de Hill): C₄₆H₈₄NO₈P
• Número CAS: 35418-59-8
• Peso molecular: 810.13
• Código UNSPSC: 51191904
• NACRES: NA.25

Propriedades

• Ensaio: >99% (TLC)
• Formulário: liquid
• embalagem: pkg of 1 × 2.5 mL (850469C-25mg); pkg of 2 × 4 mL (850469C-200mg)
• fabricante/nome comercial: Avanti Research^™ - A Croda Brand 850469C
• concentração: 10 mg/mL (850469C-25mg); 25 mg/mL (850469C-200mg)
• tipo de lipídio: phospholipids; cardiolipins
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• InChI: 1S/C46H84NO8P/c1-6-8-10-12-14-16-18-20-22-23-25-27-29-31-33-35-37-39-46(49)55-44(43-54-56(50,51)53-41-40-47(3,4)5)42-52-45(48)38-36-34-32-30-28-26-24-21-19-17-15-13-11-9-7-2/h14,16,20,22,25,27,31,33,44H,6-13,15,17-19,21,23-24,26,28-30,32,34-43H2,1-5H3/b16-14-,22-20-,27-25-,33-31-/t44-/m1/s1
• chave InChI: PSVRFUPOQYJOOZ-QNPWAGBNSA-N

Descrição

Descrição geral

18:0-20:4 Phosphatidylcholine (PC) has saturated (18:0) chain in the sn-1 position and unsaturated (20:4) in the sn-2 position. Asymmetric combinations of PC is common among mammalian lipids. PC is a zwitterionic phospholipid. PC is synthesized by Kennedy pathway from choline.

Aplicação

18:0-20:4 PC is suitable for use:

• in the preparation of liposomes
• in the synthesis of diacylglycerol
• as substrate to determine the activity of phospholipase A2 (PLA2)

Ações bioquímicas/fisiológicas

18:0-20:4 phosphatidylcholine (PC) is more prominent in specialized membranes like synaptic vesicles. Phosphatidylcholine is one of the major glycerophospholipids of the eukaryotic membranes. It is essential for maintaining the structure and functions of the membrane. PC is the precursor for various second messenger like phosphatidic acid, lysophosphatidic acid, diacylglycerol.

Embalagem

5 mL Clear Glass Sealed Ampule (850469C-200mg)

5 mL Clear Glass Sealed Ampule (850469C-25mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informações de segurança

• Pictogramas: GHS06,GHS08
• Palavra indicadora: Danger
• Frases de perigo: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• Declarações de precaução: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Classificações de perigo: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Órgãos-alvo: Central nervous system, Liver,Kidney
• Código de classe de armazenamento: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): does not flash
• Ponto de fulgor (°C): does not flash