700070P

trihydroxycholestanoic acid

Avanti Research^™ - A Croda Brand

• Sinônimo(s): 3α,7α,12α-trihydroxycholestanoic acid
• Fórmula empírica (Notação de Hill): C₂₇H₄₆O₅
• Número CAS: 547-98-8
• Peso molecular: 450.65
• Número MDL: MFCD23103336
• Código UNSPSC: 12352211
• NACRES: NA.25

Propriedades

• Ensaio: >99% (TLC)
• Formulário: powder
• embalagem: pkg of 1 × 1 mg (700070P-1mg)
• fabricante/nome comercial: Avanti Research^™ - A Croda Brand
• tipo de lipídio: bile acids
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: O[C@H]1[C@@H]2[C@@H]([C@@]4([C@H](C1)C[C@@H](CC4)O)C)C[C@@H]([C@]3([C@H]2CC[C@@H]3[C@@H](CCCC(C)C(=O)O)C)C)O
• InChI: 1S/C27H46O5/c1-15(6-5-7-16(2)25(31)32)19-8-9-20-24-21(14-23(30)27(19,20)4)26(3)11-10-18(28)12-17(26)13-22(24)29/h15-24,28-30H,5-14H2,1-4H3,(H,31,32)/t15-,16?,17+,18-,19-,20+,21+,22-,23+,24+,26+,27-/m1/s1
• chave InChI: CNWPIIOQKZNXBB-VCVMUKOKSA-N

Descrição

Descrição geral

Trihydroxycholestanoic acid (THCA) is an oxidative metabolite of cholesterol and a precursor to bile acids. Very long-chain acyl-CoA synthetase (VLCS) associated with endoplasmic reticulum and peroxisomes activates THCA, the C27 bile acid intermediate.

Aplicação

Trihydroxycholestanoic acid has been used as a sterol to test its reactivity with human mincle protein.

Ações bioquímicas/fisiológicas

Trihydroxycholestanoic acid (THCA) and dihydroxycholestanoic (DHCA) accumulation is observed in Zellweger syndrome and cholestatic liver disease. The synthesis of (25R)-isomer of DHCA and THCA is favored by mitochondrial 27-hydroxylase.

Embalagem

5 mL Amber Glass Screw Cap Vial (700070P-1mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): No data available
• Ponto de fulgor (°C): No data available