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Documentos Principais

K2755

Sigma-Aldrich

2-Keto-3-deoxyoctonate ammonium salt

≥97%

Sinônimo(s):

3-Deoxyoctulosonic acid, KDO

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About This Item

Fórmula linear:
C8H14O8 · NH3
Número CAS:
Peso molecular:
255.22
Número MDL:
Código UNSPSC:
12352100
ID de substância PubChem:
NACRES:
NA.22

Nível de qualidade

Ensaio

≥97%

Formulário

powder

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

N.OCC(O)C1OC(O)(CC(O)C1O)C(O)=O

InChI

1S/C8H14O8.H3N/c9-2-4(11)6-5(12)3(10)1-8(15,16-6)7(13)14;/h3-6,9-12,15H,1-2H2,(H,13,14);1H3

chave InChI

UDJBBKGYARWWNJ-UHFFFAOYSA-N

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Aplicação

  • Synthesis of KDO Analogues: A significant study focused on the synthesis of analogues of 3-deoxy-D-manno-octulosonic acid (KDO), which includes compounds such as 2-Keto-3-deoxyoctonate ammonium salt. These analogues were evaluated as potential inhibitors of CMP-KDO synthetase, playing a critical role in the development of new therapeutic agents targeting bacterial infections and enhancing understanding of bacterial lipopolysaccharide synthesis (Luthman et al., 1987).

Ações bioquímicas/fisiológicas

KDO is a sialic acid that is a component of bacterial lipopolysaccharides and a possible target for antibiotic development.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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