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H20806

Sigma-Aldrich

4-Hydroxybenzyl alcohol

99%

Sinônimo(s):

NSC 227926

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About This Item

Fórmula linear:
HOC6H4CH2OH
Número CAS:
623-05-2
Peso molecular:
124.14
Beilstein:
1858967
Número CE:
210-768-0
Número MDL:
MFCD00004658
Código UNSPSC:
12164502
ID de substância PubChem:
24895499
NACRES:
NA.22

Ensaio

99%

forma

powder or crystals

adequação da reação

reagent type: cross-linking reagent

pf

114-122 °C (lit.)

cadeia de caracteres SMILES

OCc1ccc(O)cc1

InChI

1S/C7H8O2/c8-5-6-1-3-7(9)4-2-6/h1-4,8-9H,5H2

chave InChI

BVJSUAQZOZWCKN-UHFFFAOYSA-N

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Descrição geral

4-Hydroxybenzyl alcohol (HBA) is a phenolic compound found in Gastrodia elata. It is an antioxidant and anti-asthmatic agent.HBA can also be used as a precursor to synthesize hydrogen peroxide-responsive copolyoxalate nanoparticles and polymers.

Aplicação

4-Hydroxybenzyl alcohol can be used as a precursor for the synthesis of:
  • HBA-incorporated copolyoxalate (HPOX) nanoparticles as potential drug delivery system.
  • Poly(4-hydroxybenzyl alcohol) by enzyme catalyzed reaction.
  • 4-Hydroxybenzyl imidazole derivatives.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H319,H412

Classificações de perigo

Aquatic Chronic 3 - Eye Irrit. 2

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análise (COA)

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Enzyme mediated oxidative polymerization of 4-hydroxybenzyl alcohol for optical applications.
Kumar V, et al.
Journal of Macromolecular Science, Part A: Pure and Applied Chemistry, 39(10), 1183-1193 (2002)
Synthesis and biochemical evaluation of a range of sulfonated derivatives of 4-hydroxybenzyl imidazole as highly potent inhibitors of rat testicular 17α-hydroxylase/17, 20-lyase (P-45017α).
Ahmed S, et al.
Bioorganic & Medicinal Chemistry Letters, 19(16), 4698-4701 (2009)
Kyung-Yoon Kam et al.
Molecules and cells, 31(3), 209-215 (2011-02-25)
The therapeutic goal in treating cerebral ischemia is to reduce the extent of brain injury and thus minimize neurological impairment. We examined the effects of p-hydroxybenzyl alcohol (HBA), an active component of Gastrodia elata Blume, on transient focal cerebral ischemia-induced
Zheng Cai et al.
Journal of drug targeting, 16(2), 178-184 (2008-02-16)
Both borneol and gastrodin are bioactive substances derived from traditional Chinese medicine. In this paper, the effect of borneol on the distribution of gastrodin to the brain in mice via oral administration was investigated. Gastrodin concentrations in plasma and gastrodigenin
M W Laschke et al.
British journal of pharmacology, 163(4), 835-844 (2011-03-04)
4-Hydroxybenzyl alcohol (HBA) is a phenolic plant compound, which has been shown to influence many cellular mechanisms. In the present study, we analysed in vitro and in vivo the anti-angiogenic actions of this pleiotropic agent. Migration and protein expression of
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