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G6600

Sigma-Aldrich

Glycine methyl ester hydrochloride

99%, for peptide synthesis

Sinônimo(s):

Glycine methyl ester·HCl, Methyl glycinate hydrochloride

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About This Item

Fórmula linear:
NH2CH2COOCH3 · HCl
Número CAS:
5680-79-5
Peso molecular:
125.55
Beilstein:
3593644
Número CE:
227-139-1
Número MDL:
MFCD00012870
Código UNSPSC:
12352209
eCl@ss:
32160406
ID de substância PubChem:
24895262
NACRES:
NA.22

Nome do produto

Glycine methyl ester hydrochloride, 99%

Nível de qualidade

200

Ensaio

99%

Formulário

powder, crystals or chunks

adequação da reação

reaction type: solution phase peptide synthesis

cor

white

pf

175 °C (dec.) (lit.)

aplicação(ões)

peptide synthesis

cadeia de caracteres SMILES

Cl.COC(=O)CN

InChI

1S/C3H7NO2.ClH/c1-6-3(5)2-4;/h2,4H2,1H3;1H

chave InChI

COQRGFWWJBEXRC-UHFFFAOYSA-N

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Descrição geral

Glycine methyl ester hydrochloride, also known as methyl glycinate hydrochloride, is a derivative of glycine, used in the preparation of amino acids and organic compounds.

Aplicação

Glycine methyl ester hydrochloride is used to synthesize cyclophosphazene compounds with amino acid esters as side groups. Additionally, it can be utilized to synthesize peptides in aqueous medium, which makes it a green method for peptide formation.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

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Certificados de análise (COA)

Lot/Batch Number
STBJ6067
STBH3052
STBF7840V
STBD9571V
STBD8245V

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Sigma-Aldrich

608165

Glycine-13C2,15N ethyl ester hydrochloride

L-Leucine methyl ester hydrochloride 98%

Sigma-Aldrich

L1002

L-Leucine methyl ester hydrochloride

tert-Butyl glycinate for synthesis

Sigma-Aldrich

8.18213

tert-Butyl glycinate

Akihiko Tohri et al.
European journal of biochemistry, 271(5), 962-971 (2004-03-11)
To elucidate the domains on the extrinsic 23 kDa protein involved in electrostatic interaction with the extrinsic 33 kDa protein in spinach photosystem II, we modified amino or carboxyl groups of the 23 kDa protein to uncharged methyl ester groups
Wenzhong Gao et al.
Organic letters, 7(19), 4241-4244 (2005-09-09)
[reaction: see text] A novel Cu(I)-catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylides with acrylates has been developed. Up to 98/2 exo/endo selectivity and up to 98% enantiomeric excess have been achieved.
Glycine enolates: the large effect of iminium ion formation on alpha-amino carbon acidity.
A Rios et al.
Journal of the American Chemical Society, 123(32), 7949-7950 (2001-08-09)
L P Roguin et al.
The Biochemical journal, 224(2), 535-540 (1984-12-01)
Bovine somatotropin with an increasing number of its carboxylate groups modified by reaction with glycine methyl ester in the presence of a water-soluble carbodi-imide was tested for its activity in different bioassays. Only those derivatives which were known to be
J M Delfino et al.
International journal of peptide and protein research, 21(4), 440-450 (1983-04-01)
The reactivity of the carboxyl groups in bovine growth hormone was studied by reaction with 1-ethyl-3(3-dimethylaminopropyl) carbodiimide in the presence of an excess of glycinemethylester. Localization in the molecule of the various kinetically distinguishable carboxyl groups was achieved. Highest reactivity
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