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D2388

Sigma-Aldrich

Dimethyl 3,3′-dithiopropionimidate dihydrochloride

powder

Sinônimo(s):

DTBP, Dimethyl 3,3′-dithio-bis(propionimidate) dihydrochloride, Wang/Richards’ reagent

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About This Item

Fórmula empírica (Notação de Hill):
C8H16N2O2S2 · 2HCl
Número CAS:
38285-78-8
Peso molecular:
309.28
Número MDL:
MFCD00043245
Código UNSPSC:
12352116
ID de substância PubChem:
57654084
NACRES:
NA.22

Formulário

powder

Nível de qualidade

100

adequação da reação

reagent type: cross-linking reagent

solubilidade

H2O: 50 mg/mL

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

Cl.Cl.COC(=N)CCSSCCC(=N)OC

InChI

1S/C8H16N2O2S2.2ClH/c1-11-7(9)3-5-13-14-6-4-8(10)12-2;;/h9-10H,3-6H2,1-2H3;2*1H

chave InChI

CQBCVFHLZAVNPF-UHFFFAOYSA-N

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Aplicação

A homobifunctional, cleavable cross-linking reagent. Typically, reacted with primary amines in the pH range 7.0-10.0 to form amidine bonds.
Reactant for:
  • Synthesis of glutathione-sensitive cross-linked polyethylenimine gene vector
  • Preparation of cyclodextrin-containing polymers designed for gene delivery
  • Crosslinking of chick oviduct progesterone-receptor subunits

Atenção

The reagant is readily hydrolyzed at neutral pH. Avoid use of reducing agents during coupling reactions.

Outras notas

Note that the amidine linkage preserves original primary amine positive charge. The disulfide linkage is cleavable by mild reduction. Incorporates an eight atom linker.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H315

Classificações de perigo

Skin Irrit. 2

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análise (COA)

Lot/Batch Number
MKCK3158
MKCK3156
MKCG2165
MKCD7400
MKCB1770V

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