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Merck
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Documentos Principais

B11702

Sigma-Aldrich

Benzoxazole

greener alternative

98%

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About This Item

Fórmula empírica (Notação de Hill):
C7H5NO
Número CAS:
Peso molecular:
119.12
Número CE:
Número MDL:
Código UNSPSC:
12352100
ID de substância PubChem:
NACRES:
NA.22

Ensaio

98%

Formulário

solid

pontuação do produto alternativo mais ecológico

old score: 8
new score: 1
Find out more about DOZN™ Scoring

características do produto alternativo mais ecológico

Waste Prevention
Safer Solvents and Auxiliaries
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

p.e.

182 °C (lit.)

pf

27-30 °C (lit.)

categoria alternativa mais ecológica

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

c1ccc2ocnc2c1

InChI

1S/C7H5NO/c1-2-4-7-6(3-1)8-5-9-7/h1-5H

chave InChI

BCMCBBGGLRIHSE-UHFFFAOYSA-N

Descrição geral

We are committed to bringing you Greener Alternative Products, which adhere to one of the four categories of Greener Alternatives . This product belongs to category of Re-engineered products, showing key improvements in Green Chemistry Principles “Waste Prevention”, “Safer Solvents and Auxiliaries” and “Enhanced Energy Efficiency”. Click here to view its DOZN scorecard.

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

136.4 °F - closed cup

Ponto de fulgor (°C)

58 °C - closed cup

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves


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A series of N-(2-(3,5-dimethoxyphenyl)benzoxazole-5-yl)benzamide derivatives (3am) was synthesized and evaluated for their in vitro inhibitory activity against COX-1 and COX-2. The compounds with considerable in vitro activity (IC50  < 1 μM) were evaluated in vivo for their anti-inflammatory potential by the carrageenan-induced
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Long-term potentiation (LTP) is a molecular basis of memory formation. Here, we demonstrate that LTP critically depends on fructose 1,6-bisphosphatase 2 (Fbp2)-a glyconeogenic enzyme and moonlighting protein protecting mitochondria against stress. We show that LTP induction regulates Fbp2 association with

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