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Merck
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Documentos Principais

81323

Sigma-Aldrich

Poly(ethylene glycol) methyl ether

average MN 5,000, methoxy, hydroxyl

Sinônimo(s):

Polyethylene glycol, Methoxy poly(ethylene glycol), Polyethylene glycol monomethyl ether, mPEG

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About This Item

Fórmula linear:
CH3(OCH2CH2)nOH
Número CAS:
Número MDL:
Código UNSPSC:
12162002
ID de substância PubChem:
NACRES:
NA.23

Nome do produto

Poly(ethylene glycol) methyl ether, average Mn 5,000

densidade de vapor

>1 (vs air)

Nível de qualidade

pressão de vapor

0.05 mmHg ( 20 °C)

Formulário

flakes
powder or crystals

peso molecular

average Mn 5,000

pf

60-64 °C

Ω-final

hydroxyl

α-final

methoxy

cadeia de caracteres SMILES

O(CCO)C

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

chave InChI

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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Aplicação

Poly(ethylene glycol) methyl ether (mPEG) is a hydrophilic polymer that is used to control the flexibility of a composite. mPEG can be used for a variety of applications such as drug delivery, tissue engineering, and other biological uses.

Outras notas

Polymer used in the polymer-supported liquid synthesis of oligosaccharides

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

359.6 °F - closed cup

Ponto de fulgor (°C)

182 °C - closed cup

Equipamento de proteção individual

Eyeshields, Gloves


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Hamed Nosrati et al.
Pharmaceutical development and technology, 24(1), 89-98 (2018-01-09)
In this study, we designed a polymersome system for the controlled release of methotrexate (MTX) as an anticancer drug with the objective of improving the loading efficiency of the drug in polymersomes as well as achievement of an efficient control
Kangan Li et al.
International journal of nanomedicine, 8, 2589-2600 (2013-07-28)
Development of dual-mode or multi-mode imaging contrast agents is important for accurate and self-confirmatory diagnosis of cancer. We report a new multifunctional, dendrimer-based gold nanoparticle (AuNP) as a dual-modality contrast agent for magnetic resonance (MR)/computed tomography (CT) imaging of breast
Yvonne K Girard et al.
PloS one, 8(10), e75345-e75345 (2013-10-23)
The development of a suitable three dimensional (3D) culture system for anticancer drug development remains an unmet need. Despite progress, a simple, rapid, scalable and inexpensive 3D-tumor model that recapitulates in vivo tumorigenesis is lacking. Herein, we report on the
Synthesis and characterization of triblock copolymers of methoxy poly (ethylene glycol) and poly (propylene fumarate)
Behravesh E, et al.
Biomacromolecules, 3(1), 153-158 (2002)
Magnetite nanoparticles stabilized with polymeric bilayer of poly (ethylene glycol) methyl ether-poly (?-caprolactone) copolymers
Meerod S, et al.
Polymer, 49(18), 3950-3956 (2008)

Artigos

Fouling Resistant Biomimetic Poly(Ethylene Glycol) Based Grafted Polymer Coatings

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

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