202509
Poly(ethylene glycol) methyl ether
average Mn 2,000, methoxy, hydroxyl
Sinônimo(s):
Polyethylene glycol, Methoxy poly(ethylene glycol), Polyethylene glycol monomethyl ether, mPEG
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About This Item
Fórmula linear:
CH3(OCH2CH2)nOH
Número CAS:
Número MDL:
Código UNSPSC:
12162002
ID de substância PubChem:
NACRES:
NA.23
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product name
Poly(ethylene glycol) methyl ether, average Mn ~2,000
densidade de vapor
>1 (vs air)
Nível de qualidade
pressão de vapor
0.05 mmHg ( 20 °C)
forma
flakes (or pellets)
peso molecular
average Mn ~2,000
viscosidade
54.6 cSt(210 °F)(lit.)
temperatura de transição
Tm 52 °C
grupo funcional
hydroxyl
InChI
1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3
chave InChI
XNWFRZJHXBZDAG-UHFFFAOYSA-N
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Descrição geral
It is a Polyethylene glycol (PEG) macromer with a reactive chain end consisting of methyl ether. Etherification of the PEG chain ends can be undertaken in basic conditions by reacting it with alkyl halides. mPEG can undergo cross linking to form hydrogels; polymerization can be initiated by redox reaction or free radical initiator.
Aplicação
Poly(ethylene glycol) methyl ether-attached dendrimers can be used as carriers for anticancer drugs. This novel drug carrier has a biocompatible surface and an interior for the encapsulation of drugs.
It can be used as a pore-forming agent in the preparation of ultrafiltration membranes which are used in the removal of macromolecules.
It can also be used as a starting material in the preparation of a biodegradable amphiphilic copolymer of poly(L-alanine) with mPEG.
It can be used as a pore-forming agent in the preparation of ultrafiltration membranes which are used in the removal of macromolecules.
It can also be used as a starting material in the preparation of a biodegradable amphiphilic copolymer of poly(L-alanine) with mPEG.
Características e benefícios
Inserting poly(ethylene glycol) methyl ether (mPEG) side chain enhances the hydrophilicity and flexibility of the polymer matrix.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
359.6 °F - closed cup
Ponto de fulgor (°C)
182 °C - closed cup
Equipamento de proteção individual
Eyeshields, Gloves
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In this study, quercetin (QC) with cancer chemoprevention effect and anticancer potential was loaded into polymeric micelles of methoxy poly(ethylene glycol)-cholesterol conjugate (mPEG-Chol) in order to increase its water solubility. MPEG-Chol with lower critical micelle concentration (CMC) value (4.0 x
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