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202495

Sigma-Aldrich

Poly(ethylene glycol) methyl ether

average MN 750, methoxy, hydroxyl

Sinônimo(s):

Polyethylene glycol, Methoxy poly(ethylene glycol), Polyethylene glycol monomethyl ether, mPEG

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About This Item

Fórmula linear:
CH3(OCH2CH2)nOH
Número CAS:
9004-74-4
Número MDL:
MFCD00084416
Código UNSPSC:
12162002
ID de substância PubChem:
24852093
NACRES:
NA.23

Nome do produto

Poly(ethylene glycol) methyl ether, average Mn 750

densidade de vapor

>1 (vs air)

Nível de qualidade

200

pressão de vapor

0.05 mmHg ( 20 °C)

Formulário

paste
solid

peso molecular

average Mn 750

índice de refração

n20/D 1.459

viscosidade

10.5 cSt(210 °F)(lit.)

temperatura de transição

Tm 30 °C

densidade

1.094 g/mL at 25 °C

Ω-final

hydroxyl

α-final

methoxy

cadeia de caracteres SMILES

O(CCO)C

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

chave InChI

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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Aplicação

Poly(ethylene glycol) methyl ether can be used:
  • As a chain transfer agent to synthesize amphiphilic block copolymers by metal-free ring-opening oligomerization.
  • As a precursor to prepare retinoic acid-polyethylene glycol nanoassembly as an efficient drug delivery system.
  • To prepare diblock copolymer with polylactic acid, which can be applied in the field of tissue engineering and drug delivery.

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

359.6 °F - closed cup

Ponto de fulgor (°C)

182 °C - closed cup

Equipamento de proteção individual

Eyeshields, Gloves

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Certificados de análise (COA)

Lot/Batch Number
MKCJ4912
MKBX5833V
MKBR8584V
MKBK5064V
MKBF8451V

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Poly(ethylene glycol) methyl ether tosylate average Mn 900

Sigma-Aldrich

729116

Poly(ethylene glycol) methyl ether tosylate

Methoxypolyethylene glycol maleimide 750

Sigma-Aldrich

712558

Methoxypolyethylene glycol maleimide

Yi Wei et al.
Langmuir : the ACS journal of surfaces and colloids, 28(39), 13984-13992 (2012-09-04)
The microcosmic mechanisms of protein (recombinant human growth hormone, rhGH) incomplete release and stability from amphiphilic poly(monomethoxypolyethylene glycol-co-D,L-lactide) (mPEG-PLA, PELA) microspheres were investigated. PELA with different hydrophilicities (PELA-1, PELA-2, and PELA-3) based on various ratios of mPEG to PLA were
Prakash G Avaji et al.
Bioorganic & medicinal chemistry letters, 23(6), 1763-1767 (2013-02-16)
Saturated fatty acids (FA) were grafted using tyrosine as a spacer group to the cyclotriphosphazene ring along with equimolar hydrophilic methoxy poly(ethylene glycol) (MPEG) in cis-nongeminal way. Seven new cyclotriphosphazene amphiphiles were prepared from combinations of hydrophilic MPEGs with different
Mulu Z Tesfay et al.
Journal of virology, 87(7), 3752-3759 (2013-01-18)
We are developing oncolytic vesicular stomatitis viruses (VSVs) for systemic treatment of multiple myeloma, an incurable malignancy of antibody-secreting plasma cells that are specifically localized in the bone marrow. One of the presumed advantages for using VSV as an oncolytic
Seung-Young Lee et al.
Biomaterials, 34(2), 552-561 (2012-10-20)
Although targeted delivery mediated by ligand modified or tumor microenvironment sensitive nanocarriers has been extensively pursued for cancer chemotherapy, the efficiency is still limited by premature drug release after systemic administration. Herein we report a highly blood-stable, tumor-adaptable drug carrier
Lina Du et al.
Anti-cancer drugs, 24(2), 172-180 (2012-09-20)
A functionalized poly(amidoamine) (PAMAM) nanocarrier was designed and prepared to deliver anticancer drugs. The nanocarrier is a copolymer with a core-shell structure with 3.0 G PAMAM as the core and sequentially conjugated poly(2-(N,N-diethylamino)ethyl methacrylate) (pDEA) and methoxy-poly(ethylene glycol) 2000 (mPEG)
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