682144

(R)-(–)-4,12-Bis(diphenylphosphino)-[2.2]-paracyclophane

96%

• Sinônimo(s): (R)-Phanephos
• Fórmula empírica (Notação de Hill): C₄₀H₃₄P₂
• Número CAS: 364732-88-7
• Peso molecular: 576.65
• Número MDL: MFCD03094575
• Código UNSPSC: 12352002
• ID de substância PubChem: 24885681
• NACRES: NA.22

Propriedades

• Nível de qualidade: 100
• Ensaio: 96%
• forma: solid
• atividade óptica: [α]/D -34±4°, c = 1 in chloroform
• pf: 222-226 °C
• grupo funcional: phosphine
• InChI: 1S/C40H34P2/c1-5-13-35(14-6-1)41(36-15-7-2-8-16-36)39-29-31-21-25-33(39)27-23-32-22-26-34(28-24-31)40(30-32)42(37-17-9-3-10-18-37)38-19-11-4-12-20-38/h1-22,25-26,29-30H,23-24,27-28H2
• chave InChI: GYZZZILPVUYAFJ-UHFFFAOYSA-N

Descrição

Aplicação

(R)-(-)-4,12-Bis(diphenylphosphino)-[2.2]-paracyclophane may be used as a ligand in the following processes:

• Enantioselective reductive cyclization of 1,6-enynes via asymmetric hydrogenation in the presence of a rhodium catalyst to form alkylidene-substituted heterocycles.
• Asymmetric hydroboration of 3,3-disubstituted cyclopropenes to form 2,2-disubstituted cyclopropyl boronates.
• Asymmetric ring-opening reactions of azabenzonorbornadienes in the presence of zinc(II) triflate and palladium(II) acetate to form aminodihydronaphthalenes.

Efficient ligand for asymmetric hydrogentation of dehydroamino acids, methyl esters and keytones.

Informações legais

Sold in collaboration with Johnson Matthey Catalyst for research purposes only. US5874629 and any patents arising therefrom apply.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves