Pular para o conteúdo
Merck
Todas as fotos(3)

Key Documents

View All Documentation

550019

Sigma-Aldrich

N,N-Dimethyldipropylenetriamine

99%

Sinônimo(s):

DMAPAPA

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(3)

About This Item

Fórmula linear:
(CH3)2N(CH2)3NH(CH2)3NH
Número CAS:
10563-29-8
Peso molecular:
159.27
Número CE:
234-148-4
Número MDL:
MFCD00082192
Código UNSPSC:
12352100
ID de substância PubChem:
24879085
NACRES:
NA.22

Nível de qualidade

100

Ensaio

99%

índice de refração

n20/D 1.4630 (lit.)

pb

220 °C (lit.)

densidade

0.883 g/mL at 25 °C (lit.)

grupo funcional

amine

cadeia de caracteres SMILES

CN(C)CCCNCCCN

InChI

1S/C8H21N3/c1-11(2)8-4-7-10-6-3-5-9/h10H,3-9H2,1-2H3

chave InChI

OMKZWUPRGQMQJC-UHFFFAOYSA-N

Descrição geral

N,N-Dimethyldipropylenetriamine is an aliphatic acyclic amine that is commonly used to develop polymeric system for gene delivery.

Aplicação

N,N-Dimethyldipropylenetriamine (DP) may be used to:
  • Prepare poly(ethylene oxide)-b-poly(3-caprolactone-g-DP) [PEO-b-P(CL-g-DP)], a biodegradable amphiphilic polycationic copolymer.
  • Develop a second generation aminoglycoside 6′-N-acetyltransferase (AAC(6′) inhibitor.
  • Prepare a hydrophilic gemcitabine conjugated cationic copolymer, which can be employed in the treatment pancreatic cancer.

Informações legais

Product of Arkema Inc.

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Corr. 1A - Skin Sens. 1

Código de classe de armazenamento

8A - Combustible corrosive hazardous materials

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

210.2 °F - closed cup

Ponto de fulgor (°C)

99 °C - closed cup

Equipamento de proteção individual

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
MKCK2360
SHBJ5040
SHBH2431V
SHBG4812V
SHBG4637V

Não está vendo a versão correta?

Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.

Pesquise por COA

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Xiao-Bing Xiong et al.
Biomaterials, 30(2), 242-253 (2008-10-08)
The RNA interference (RNAi) technology has been successfully used in elucidating mechanisms behind various biological events. However, in the absence of safe and effective carriers for in vivo delivery of small interfering RNAs (siRNAs), application of this technology for therapeutic
Anupama Mittal et al.
Biomaterials, 35(25), 7077-7087 (2014-05-20)
Clinical effectiveness of gemcitabine in pancreatic cancer is hindered due to its rapid plasma metabolism and development of chemo-resistance. We have previously delineated the significant role of miRNAs in mediating the growth and proliferation of cancer stem cells (CSCs) which
Feng Gao et al.
Journal of medicinal chemistry, 49(17), 5273-5281 (2006-08-18)
Truncated aminoglycoside-coenzyme A bisubstrate analogues were efficiently prepared using a convergent approach where the amine and the thiol are coupled in one pot with the addition of a linker, without the need for protecting groups. These derivatives were tested for
[Toxicity of several aliphatic amines].
G I Sidorin et al.
Gigiena truda i professional'nye zabolevaniia, (11)(11), 50-53 (1984-11-01)
J Shen et al.
Biomaterials, 34(18), 4520-4531 (2013-03-23)
The low toxicity and efficient gene delivery of polymeric vectors remain the major barrier to the clinical application of non-viral gene therapy. Here, we present a poly-D, L-succinimide (PSI)-based biodegradable cationic polymer which mimicked the golden standard, branched polyethylenimine (PEI

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica