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Merck
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Key Documents

240230

Sigma-Aldrich

Phthalimide

≥99%

Sinônimo(s):

1,3-Dihydro-1,3-dioxoisoindole

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About This Item

Fórmula empírica (Notação de Hill):
C8H5NO2
Número CAS:
Peso molecular:
147.13
Beilstein:
118522
Número CE:
Número MDL:
Código UNSPSC:
12352100
ID de substância PubChem:
NACRES:
NA.22

Nível de qualidade

Ensaio

≥99%

pf

232-235 °C (lit.)

solubilidade

water: slightly soluble(lit.)

cadeia de caracteres SMILES

O=C1NC(=O)c2ccccc12

InChI

1S/C8H5NO2/c10-7-5-3-1-2-4-6(5)8(11)9-7/h1-4H,(H,9,10,11)

chave InChI

XKJCHHZQLQNZHY-UHFFFAOYSA-N

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Aplicação

Phthalimide was used in the synthesis of 6-amino agarose (AA) by Mitsunobu-inspired microwave mediated method.

Código de classe de armazenamento

13 - Non Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

302.0 °F - closed cup

Ponto de fulgor (°C)

150 °C - closed cup

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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Stalin Kondaveeti et al.
Carbohydrate polymers, 106, 365-373 (2014-04-12)
A facile 6-aminoagarose (AA) mediated synthesis of new fluorogenic amides of agarose with nicotinic (AA-NA) and picolinic acids (AA-PA) employing carbodiimide chemistry have been described. 6-Amino agarose (AA) was synthesized in a facile Mitsunobu-inspired microwave mediated method involving the reaction
Alessio Pierini et al.
Journal of veterinary science, 21(5), e60-e60 (2020-10-06)
Tumor-associated neoangiogenesis is a crucial target for antitumor therapies. Thalidomide (TAL) is a promising anti-neoangiogenetic drug that has recently been used in the treatment of several malignancies in dogs. The aim of the study was to assess the pharmacokinetics of
Shi Tang et al.
Organic letters, 10(6), 1179-1182 (2008-02-23)
A novel palladium-catalyzed intermolecular aminopalladation/C-H activation method for selectively synthesizing (E)-(2-oxindolin-3-ylidene)phthalimides has been developed. In the presence of Pd(OAc)2 and PhI(OAc)2, alkynes were difunctionalized with a phthalimide and an arene sp2 C-H bond to selectively synthesize (E)-(2-oxoindolin-3-ylidene)phthalimides, which products are
Barbara Weiner et al.
Journal of the American Chemical Society, 131(27), 9473-9474 (2009-07-09)
A new method for the synthesis of beta(3)-amino acids is presented. Phthalimide protected allylic amines are oxidized under Wacker conditions selectively to aldehydes using PdCl(2) and CuCl or Pd(MeCN)(2)Cl(NO(2)) and CuCl(2) as complementary catalyst systems. The aldehydes are produced in
Edward C Lawson et al.
Journal of medicinal chemistry, 52(23), 7432-7445 (2009-09-08)
We have discovered two related chemical series of nonpeptide urotensin-II (U-II) receptor antagonists based on piperazino-phthalimide (5 and 6) and piperazino-isoindolinone (7) scaffolds. These structure types are distinctive from those of U-II receptor antagonist series reported in the literature. Antagonist

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