21860

CDI

≥97.0% (T), for peptide synthesis

• Sinônimo(s): 1,1′-Carbonyldiimidazole
• Fórmula empírica (Notação de Hill): C₇H₆N₄O
• Número CAS: 530-62-1
• Peso molecular: 162.15
• Beilstein: 6826
• Número CE: 208-488-9
• Número MDL: MFCD00005286
• Código UNSPSC: 12352115
• ID de substância PubChem: 57647944
• NACRES: NA.22

Propriedades

• product name: CDI, ≥97.0% (T)
• Nível de qualidade: 200
• Ensaio: ≥97.0% (T)
• forma: solid
• adequação da reação: reaction type: Carbonylations
• pf: 115-122 °C; 117-122 °C (lit.)
• aplicação(ões): peptide synthesis
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: O=C(n1ccnc1)n2ccnc2
• InChI: 1S/C7H6N4O/c12-7(10-3-1-8-5-10)11-4-2-9-6-11/h1-6H
• chave InChI: PFKFTWBEEFSNDU-UHFFFAOYSA-N

Descrição

Descrição geral

CDI serves as a powerful coupling reagent in peptide synthesis and organic chemistry.

Aplicação

CDI (1,1′-Carbonyldiimidazole) can be used:

• In the activation of malonic acid derivatives to prepare carbonyl imidazoles by mild decarboxylation.
• In the activation of cellulose membranes for the development of immunosensors.
• In the synthesis of substituted 1,3-oxazolo[4,5-d] pyridazinones.
• As a reagent for the conversion of various hydroxamic acids to isocyanates by Lossen rearrangement.
• In the synthesis of 1,3,4-oxadiazole derivatives , and peptide thioesters in water.
• As an acylation agent for the synthesis of carbamates.

Outras notas

Reactive reagent for the activation of acids as imidazolides: synthesis of esters, amides, ketones etc. Reagent for immobilizing enzymes and affinity ligands; Carbonyl-transfer reagent for the synthesis of various heterocycles, some recent applications

Informações de segurança

• Pictogramas: GHS05,GHS07
• Palavra indicadora: Danger
• Frases de perigo: H302,H314
• Declarações de precaução: P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Classificações de perigo: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
• Código de classe de armazenamento: 8A - Combustible corrosive hazardous materials
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges