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157945

Sigma-Aldrich

(4-Carboxybutyl)triphenylphosphonium bromide

98%

Sinônimo(s):

5-(Triphenylphosphonio)pentanoic acid bromide, Carboxybutyltriphenylphosphonium bromide, NSC 147756

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About This Item

Fórmula linear:
(C6H5)3P(Br)(CH2)4COOH
Número CAS:
17814-85-6
Peso molecular:
443.31
Beilstein:
3586477
Número CE:
241-782-5
Número MDL:
MFCD00011906
Código UNSPSC:
12352107
ID de substância PubChem:
24849711
NACRES:
NA.22

Ensaio

98%

Formulário

powder

adequação da reação

reaction type: C-C Bond Formation

pf

204-207 °C (lit.)

grupo funcional

carboxylic acid
phosphine

cadeia de caracteres SMILES

[Br-].OC(=O)CCCC[P+](c1ccccc1)(c2ccccc2)c3ccccc3

InChI

1S/C23H23O2P.BrH/c24-23(25)18-10-11-19-26(20-12-4-1-5-13-20,21-14-6-2-7-15-21)22-16-8-3-9-17-22;/h1-9,12-17H,10-11,18-19H2;1H

chave InChI

MLOSJPZSZWUDSK-UHFFFAOYSA-N

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Aplicação

  • Used as a platform for delivery of pro-apoptotic peptides into the mitochondria of tumor cells

Reactant for preparation of:
  • Ring skeletons via ring closing metathesis and double bond migration ring closing metathesis reactions
  • Methyl alkenyl quinolones as antimycobacterial agents
  • Prostaglandins and their drug analogs via Gold-catalyzed Meyer-Schuster rearrangement
  • Diphenylmethylpiperazines as N-type calcium channel blockers as potential therapeutic agents
  • Folate receptor-specific glycinamide ribonucleotide formyltransferase (GARFTase) inhibitors with antitumor activity
  • Cycloalkylidene alkanols with antileishmanial activity, via Wittig reaction

Pictogramas

Skull and crossbonesCorrosion
GHS06,GHS05

Palavra indicadora

Danger

Frases de perigo

H301,H318

Classificações de perigo

Acute Tox. 3 Oral - Eye Dam. 1

Código de classe de armazenamento

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análise (COA)

Lot/Batch Number
STBH0658
0000217293
STBH0658
0000184026
0000118461

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