126268
2,4-Dihydroxypyrimidine-5-carboxylic acid
95%
Sinônimo(s):
Isoorotic acid, Uracil-5-carboxylic acid
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About This Item
Fórmula empírica (Notação de Hill):
C5H4N2O4
Número CAS:
Peso molecular:
156.10
Número CE:
Número MDL:
Código UNSPSC:
12352100
ID de substância PubChem:
NACRES:
NA.22
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Nível de qualidade
Ensaio
95%
forma
powder
pf
283 °C (dec.) (lit.)
grupo funcional
carboxylic acid
cadeia de caracteres SMILES
OC(=O)C1=CNC(=O)NC1=O
InChI
1S/C5H4N2O4/c8-3-2(4(9)10)1-6-5(11)7-3/h1H,(H,9,10)(H2,6,7,8,11)
chave InChI
ZXYAAVBXHKCJJB-UHFFFAOYSA-N
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Descrição geral
2,4-Dihydroxypyrimidine-5-carboxylic acid (Uracil-5-carboxylic acid) has been obtained from 5-formyluracil by the action of enzyme, thymine 7-hydroxylase. It has been used to synthesize N1-alkylated uracil derivatives.
Aplicação
2,4-Dihydroxypyrimidine-5-carboxylic acid (Uracil-5-carboxylic acid) has been used for the visual sensing of melamine (at parts-per-billion (ppb) level) by a highly sensitive analytical method based on Au nanoparticles.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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P M Shaffer et al.
Journal of bacteriology, 121(2), 648-655 (1975-02-01)
The experiments in this report involve the following series of reactions which were previously demonstrated with purified enzyme preparations from Neurospora crassa: thymidine a yields thymine ribonucleoside b yields thymine c yields 5-hydroxymethyluracil d yields 5-formyluracil e yields uracil-5-carboxylic acid
Raj Kumar Bera et al.
The Analyst, 136(8), 1644-1648 (2011-02-25)
A highly sensitive analytical method based on Au nanoparticles rationally tailored with recognition elements uracil-5-carboxylic acid (UCA) and 2,4,6-trinitrobenzenesulfonic acid (TNBS) for the visual sensing of melamine at the parts-per-billion (ppb) level is described. The tailored Au nanoparticles function as
Alessandro Accetta et al.
Journal of medicinal chemistry, 52(1), 87-94 (2008-12-17)
The synthesis of C5 linked uracil dimers was carried out according to a model developed in order to bind adenine in DNA. N1-Alkylated uracil derivatives were synthesized from isoorotic acid (uracil-5-carboxylic acid) or thymine. The carboxylic acid derivatives were condensed
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