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Merck

ADORA3

adenosine A3 receptor

Sinônimos:
A3AR, AD026, bA552M11.5
Espécies:
ID UniProtKB:
ID do gene:
  • Human(140) Summary: This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(11542) adenosine A3 receptor
  • Rat(25370) adenosine A3 receptor
  • chicken(373956) adenosine A3 receptor
  • domestic cat(101094689) adenosine A3 receptor
  • dog(403805) adenosine A3 receptor
  • cow(780806) adenosine A3 receptor
  • sheep(443330) adenosine A3 receptor
  • Domestic Rabbit(100008725) adenosine A3 receptor
  • naked mole-rat(101697269) adenosine A3 receptor
  • domestic guinea pig(100725432) adenosine A3 receptor

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Small Molecule - Agonist

Número do produto
Descrição
Espécies
Adenosine, ,
Espécies
human
Formycin A, from Streptomyces kaniharaensis, ≥98% (HPLC),
Espécies
human
Adenosine, phyproof® Reference Substance,
Espécies
human
Adenosine, Pharmaceutical Secondary Standard; Certified Reference Material,
Espécies
human
AB-MECA, solid,
Espécies
human, rat

Small Molecule - Antagonist

Número do produto
Descrição
Espécies
VUF 5574, ,
Espécies
human
Tyramine hydrochloride, ≥98%,
Espécies
human
(S)-(−)-Bay K8644, ≥98% (HPLC), solid,
Espécies
human, rat
3-Deazaadenosine, ,
Espécies
rat
Cafeína, Pharmaceutical Secondary Standard; Certified Reference Material,
Espécies
human

Antibodies

Número do produto
Descrição
Reatividade de espécies
Aplicação
Anti-Adenosine A3 Receptor Antibody, extracellular (a.a. 154-168), Chemicon®, from rabbit,
Reatividade de espécies
rat
Aplicação
ELISA
immunocytochemistry

western blot
Monoclonal Anti-ADORA3 antibody produced in mouse, clone 1A3, purified immunoglobulin, buffered aqueous solution,
Reatividade de espécies
human
Aplicação
ELISA
Anti-ADORA3 antibody produced in rabbit, affinity isolated antibody,
Reatividade de espécies
human, mouse, rat
Aplicação
ELISA
immunofluorescence

Small Molecule - Inhibitor

Número do produto
Descrição
Espécies
EHNA hydrochloride, ≥98% (HPLC),
Espécies
human
Dilazep dihydrochloride, powder,
Espécies
human
5′-Deoxy-5′-(methylthio)adenosine, ,
Espécies
human, rat, mouse
α-Naphthoflavone, ≥98%,
Espécies
human, rat
Galangin, autophagy inducing flavonoid,
Espécies
human, rat

Small Molecule - Ligand

Número do produto
Descrição
Espécies
2-Chloro-2′-deoxyadenosine, antileukemic,
Espécies
rat, human
1,7-Dimethylxanthine, ~98%, solid,
Espécies
rat, human
Chloro-IB-MECA, solid, ≥98% (HPLC),
Espécies
human, rat
Adenosine, ≥99%,
Espécies
human, rat
Theophylline, anhydrous, ≥99%, powder,
Espécies
mouse, human, rat

Small Molecule - Mixed Agonist/Antagonist

Número do produto
Descrição
Espécies
2-Iodoadenosine, 97%,
Espécies
human, rat
2-Fluoroadenine-9-β-D-arabinofuranoside, DNA synthesis and methylation inhibitor,
Espécies
rat, human
2-Fluoroadenosine, 97%,
Espécies
rat, human
2-Chloroadenosine, ,
Espécies
human, rat
Chloro-IB-MECA, solid, ≥98% (HPLC),
Espécies
human, rat

esiRNA

Número do produto
Descrição
Espécies
MISSION® esiRNA, targeting human ADORA3,
Espécies
human
MISSION® esiRNA, targeting human TMIGD3,
Espécies
human