TGIF1
TGFB-induced factor homeobox 1
Synonyms:
HPE4, TGIF
Species:
Human TGIF1 (7050), Mouse Tgif1 (21815), Rat Tgif1 (316742), Zebrafish tgif1 (321756), chicken TGIF1 (396339), dog TGIF1 (490537), domestic cat TGIF1 (101084747), domestic guinea pig Tgif1 (100716233), naked mole-rat Tgif1 (101698504), cow TGIF1 (510050)
UniProtKB ID:
Gene ID:
- Human(7050) Summary: The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and multiple splice variants encoding distinct isoforms are described. [provided by RefSeq, Jul 2013]
- Mouse(21815) TGFB-induced factor homeobox 1
- Rat(316742) TGFB-induced factor homeobox 1
- Zebrafish(321756) TGFB-induced factor homeobox 1
- chicken(396339) TGFB-induced factor homeobox 1
- dog(490537) TGFB-induced factor homeobox 1
- domestic cat(101084747) TGFB-induced factor homeobox 1
- domestic guinea pig(100716233) TGFB-induced factor homeobox 1
- naked mole-rat(101698504) TGFB-induced factor homeobox 1
- cow(510050) TGFB-induced factor homeobox 1
- sheep(101105544) TGFB-induced factor homeobox 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-TGIF antibody produced in mouse, clone 1D12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-TGIF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot