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Merck

SORCS1

sortilin-related VPS10 domain containing receptor 1

Synonyms:
hSorCS
Species:
UniProtKB ID:
Gene ID:
  • Human(114815) Summary: This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins; it is not yet known if this encoded protein is also a preproprotein. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(58178) VPS10 domain receptor protein SORCS 1
  • Rat(309533) sortilin-related VPS10 domain containing receptor 1
  • Zebrafish(100332340) sortilin-related VPS10 domain containing receptor 1
  • chicken(423885) sortilin-related VPS10 domain containing receptor 1
  • Horse(100069383) sortilin-related VPS10 domain containing receptor 1
  • domestic cat(101097844) sortilin-related VPS10 domain containing receptor 1
  • dog(477816) sortilin-related VPS10 domain containing receptor 1
  • domestic guinea pig(100719252) sortilin-related VPS10 domain containing receptor 1
  • naked mole-rat(101720277) sortilin-related VPS10 domain containing receptor 1
  • cow(537536) sortilin-related VPS10 domain containing receptor 1
  • sheep(101116272) sortilin-related VPS10 domain containing receptor 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SORCS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SORCS1,
Species
human