RGS18
regulator of G-protein signaling 18
Synonyms:
RGS13
Species:
Human RGS18 (64407), Mouse Rgs18 (64214), Rat Rgs18 (289076), Zebrafish rgs18 (768164), domestic cat RGS18 (101089487), dog RGS18 (607858), chicken RGS18 (424361), cow RGS18 (613624), sheep RGS18 (101123221), domestic guinea pig Rgs18 (100716189)
UniProtKB ID:
Gene ID:
- Human(64407) Summary: This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
- Mouse(64214) regulator of G-protein signaling 18
- Rat(289076) regulator of G-protein signaling 18
- Zebrafish(768164) regulator of G-protein signaling 18
- domestic cat(101089487) regulator of G-protein signaling 18
- dog(607858) regulator of G-protein signaling 18
- chicken(424361) regulator of G-protein signaling 18
- cow(613624) regulator of G-protein signaling 18
- sheep(101123221) regulator of G-protein signaling 18
- domestic guinea pig(100716189) regulator of G-protein signaling 18
- naked mole-rat(101702279) regulator of G-protein signaling 18
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-RGS18 antibody produced in mouse, clone 1G12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-RGS18 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-RGS18 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, human, rat
Application
western blot
Anti-RGS18 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-RGS18 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
esiRNA
Product Number
Description
Species