NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
Synonyms:
ALPS4, N-ras, NRAS1, NS6
Species:
Human NRAS (4893), Mouse Nras (18176), Rat Nras (24605), Zebrafish nras (30380), cow NRAS (506322), dog NRAS (403872), chicken NRAS (419885), sheep NRAS (101102438), domestic guinea pig Nras (100135584), naked mole-rat Nras (101719269)
UniProtKB ID:
Gene ID:
- Human(4893) Summary: This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011]
- Mouse(18176) neuroblastoma ras oncogene
- Rat(24605) neuroblastoma ras oncogene
- Zebrafish(30380) neuroblastoma RAS viral (v-ras) oncogene homolog
- cow(506322) neuroblastoma RAS viral (v-ras) oncogene homolog
- dog(403872) neuroblastoma RAS viral (v-ras) oncogene homolog
- chicken(419885) neuroblastoma RAS viral (v-ras) oncogene homolog
- sheep(101102438) neuroblastoma RAS viral (v-ras) oncogene homolog
- domestic guinea pig(100135584) neuroblastoma ras oncogene
- naked mole-rat(101719269) neuroblastoma RAS viral (v-ras) oncogene homolog
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-N-RAS antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Monoclonal Anti-NRAS antibody produced in mouse, clone 2A3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-N-RAS antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP174, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-NRAS (C-terminal) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human
Application
western blot
Anti-KRAS+HRAS+NRAS Antibody, clone 6S6F3, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunofluorescence
western blot
western blot