NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
Synonyms:
NF-ATC, NFAT2, NFATc
Species:
Human NFATC1 (4772), Mouse Nfatc1 (18018), Rat Nfatc1 (100361818), Domestic Rabbit NFATC1 (100352378), naked mole-rat Nfatc1 (101697946), domestic guinea pig Nfatc1 (100730044), sheep NFATC1 (101108097), Zebrafish nfatc1 (568315), cow NFATC1 (511224), Horse NFATC1 (100065378) ...More
UniProtKB ID:
Gene ID:
- Human(4772) Summary: The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. [provided by RefSeq, Jul 2013]
- Mouse(18018) nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
- Rat(100361818) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
- Domestic Rabbit(100352378) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
- naked mole-rat(101697946) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
- domestic guinea pig(100730044) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
- sheep(101108097) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
- Zebrafish(568315) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
- cow(511224) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
- Horse(100065378) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
- domestic cat(101101259) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
- dog(483925) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
- chicken(420815) nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
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Small Molecule - Antagonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-NFATC1 (ab1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-NFATC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-NFAT2 Antibody, clone 4I9P10, Rabbit Monoclonal, ,
Species Reactivity
mouse
Application
western blot
Anti-NFATc1 Antibody, clone 1O16 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
ELISA
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot