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Merck

MTOR

mechanistic target of rapamycin (serine/threonine kinase)

別名:
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Species:
Human MTOR (2475), Mouse Mtor (56717), Rat Mtor (56718), Zebrafish mtor (324254), cow MTOR (100139219), Horse MTOR (100051341), domestic cat MTOR (101098152), dog MTOR (478232), fruit fly Mtor (36264), chicken MTOR (419455) ...詳細
UniProtKB ID:
P42345, Q4LE76, Q5TER1, Q6LE87, Q96QG3, Q9Y4I3
遺伝子ID:
  • Human(2475) Summary: The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]
  • Mouse(56717) mechanistic target of rapamycin (serine/threonine kinase)
  • Rat(56718) mechanistic target of rapamycin (serine/threonine kinase)
  • Zebrafish(324254) mechanistic target of rapamycin (serine/threonine kinase)
  • cow(100139219) mechanistic target of rapamycin (serine/threonine kinase)
  • Horse(100051341) mechanistic target of rapamycin (serine/threonine kinase)
  • domestic cat(101098152) mechanistic target of rapamycin (serine/threonine kinase)
  • dog(478232) mechanistic target of rapamycin (serine/threonine kinase)
  • fruit fly(36264) Megator
  • chicken(419455) mechanistic target of rapamycin (serine/threonine kinase)
  • Domestic Rabbit(100356164) mechanistic target of rapamycin (serine/threonine kinase)
  • naked mole-rat(101725626) mechanistic target of rapamycin (serine/threonine kinase)
  • domestic guinea pig(100724938) mechanistic target of rapamycin (serine/threonine kinase)
  • Goat(100860902) mechanistic target of rapamycin (serine/threonine kinase)
  • sheep(100271659) mechanistic target of rapamycin (serine/threonine kinase)

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Antibodies

製品番号
詳細
交差性
アプリケーション
OP97
Anti-mTOR/FRAP (Ab-2) Mouse mAb (22C2), liquid, clone 22C2, Calbiochem®,
交差性
human
アプリケーション
SAB4504476
Anti-phospho-mTOR (pSer2448) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunohistochemistry
western blot
09-213
Anti-phospho-mTOR (Ser2448) Antibody, Upstate®, from rabbit,
交差性
human
アプリケーション
western blot
05-1592
Anti-mTOR Antibody, clone 21D8.2, clone 2ID8.2, from mouse,
交差性
human, mouse
アプリケーション
immunocytochemistry
western blot
SAB4301526
Anti-phospho-mTOR (pSer2481) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
SML0120
ペルヘキシリン マレイン酸塩, ≥98% (HPLC),
Species
human
PZ0235
PF-04691502, ≥98% (HPLC),
Species
human

Proteins

製品番号
詳細
Species
14-770-M
mTOR (1362-end) Protein, active, 10 µg, Active, N-terminal FLAG-tagged, recombinant, human mTOR, amino acids 1362-end, for use in Kinase Assays.,
Species
human
SRP0364
mTOR/Raptor/MLST8 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥50% (SDS-PAGE),
Species
human

esiRNA

製品番号
詳細
Species
EHU101641
MISSION® esiRNA, targeting human MTOR,
Species
human