MTOR
mechanistic target of rapamycin (serine/threonine kinase)
Synonyms:
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Species:
Human MTOR (2475), Mouse Mtor (56717), Rat Mtor (56718), Zebrafish mtor (324254), cow MTOR (100139219), Horse MTOR (100051341), domestic cat MTOR (101098152), dog MTOR (478232), fruit fly Mtor (36264), chicken MTOR (419455) ...More
UniProtKB ID:
Gene ID:
- Human(2475) Summary: The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]
- Mouse(56717) mechanistic target of rapamycin (serine/threonine kinase)
- Rat(56718) mechanistic target of rapamycin (serine/threonine kinase)
- Zebrafish(324254) mechanistic target of rapamycin (serine/threonine kinase)
- cow(100139219) mechanistic target of rapamycin (serine/threonine kinase)
- Horse(100051341) mechanistic target of rapamycin (serine/threonine kinase)
- domestic cat(101098152) mechanistic target of rapamycin (serine/threonine kinase)
- dog(478232) mechanistic target of rapamycin (serine/threonine kinase)
- fruit fly(36264) Megator
- chicken(419455) mechanistic target of rapamycin (serine/threonine kinase)
- Domestic Rabbit(100356164) mechanistic target of rapamycin (serine/threonine kinase)
- naked mole-rat(101725626) mechanistic target of rapamycin (serine/threonine kinase)
- domestic guinea pig(100724938) mechanistic target of rapamycin (serine/threonine kinase)
- Goat(100860902) mechanistic target of rapamycin (serine/threonine kinase)
- sheep(100271659) mechanistic target of rapamycin (serine/threonine kinase)
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Antibodies
Product Number
Description
Species Reactivity
Application
Rabbit anti-mTOR Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human
Application
immunoprecipitation (IP)
proximity ligation assay
western blot
proximity ligation assay
western blot
Anti-phospho-mTOR (pSer2448) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho-mTOR (pThr2446) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Monoclonal Anti-MTOR antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL8228, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
western blot
Anti-mTOR Antibody, clone F11, clone F11, from mouse,
Species Reactivity
human, rat
Application
immunoprecipitation (IP)
western blot
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
mTOR (1362-end) Protein, active, 10 µg, Active, N-terminal FLAG-tagged, recombinant, human mTOR, amino acids 1362-end, for use in Kinase Assays.,
Species
human
mTOR/Raptor/MLST8 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥50% (SDS-PAGE),
Species
human
esiRNA
Product Number
Description
Species