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LIMS1

LIM and senescent cell antigen-like domains 1

Synonyms:
PINCH, PINCH-1, PINCH1
Species:
UniProtKB ID:
Gene ID:
  • Human(3987) Summary: The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
  • Mouse(110829) LIM and senescent cell antigen-like domains 1
  • Rat(499443) LIM and senescent cell antigen-like domains 1
  • domestic guinea pig(100735007) LIM and senescent cell antigen-like domains 1
  • naked mole-rat(101696476) LIM and senescent cell antigen-like domains 1
  • sheep(101116555) LIM and senescent cell antigen-like domains 1
  • Zebrafish(554019) LIM and senescent cell antigen-like domains 1
  • chicken(414880) LIM and senescent cell antigen-like domains 1
  • dog(474540) LIM and senescent cell antigen-like domains 1
  • Horse(100060267) LIM and senescent cell antigen-like domains 1
  • cow(540281) LIM and senescent cell antigen-like domains 1
  • domestic cat(101094258) LIM and senescent cell antigen-like domains 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-LIMS1, clone 5G7 Antibody, ascites fluid, clone 5G7, from mouse,
Species Reactivity
human
Application
ELISA
flow cytometry

immunofluorescence

western blot
Anti-Pinch-1 Antibody, clone 9D2.1, clone 9D2.1, from mouse,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Anti-LIMS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-LIMS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
Monoclonal Anti-PINCH-1 antibody produced in mouse, clone PINCH-C58, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
bovine, canine, hamster, human, monkey, mouse, rat
Application
ELISA
immunoprecipitation (IP)

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human LIMS1,
Species
human
MISSION® esiRNA, targeting mouse Lims1,
Species
mouse