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Merck

LGI1

leucine-rich, glioma inactivated 1

Synonyms:
ADLTE, ADPAEF, ADPEAF, EPITEMPIN, EPT, ETL1, IB1099
Species:
UniProtKB ID:
Gene ID:
  • Human(9211) Summary: This gene is rearranged as a result of translocations in glioblastoma cell lines. The protein contains a hydrophobic segment representing a putative transmembrane domain with the amino terminus located outside the cell. It also contains leucine-rich repeats with conserved cysteine-rich flanking sequences. This gene is predominantly expressed in neural tissues and its expression is reduced in low grade brain tumors and significantly reduced or absent in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. [provided by RefSeq, Jul 2008]
  • Mouse(56839) leucine-rich repeat LGI family, member 1
  • Rat(252892) leucine-rich, glioma inactivated 1
  • sheep(101105294) leucine-rich, glioma inactivated 1
  • Domestic Rabbit(100344253) leucine-rich, glioma inactivated 1
  • domestic guinea pig(100726518) leucine-rich, glioma inactivated 1
  • naked mole-rat(101703526) leucine-rich, glioma inactivated 1
  • chicken(423802) leucine-rich, glioma inactivated 1
  • cow(617080) leucine-rich, glioma inactivated 1
  • domestic cat(101088030) leucine-rich, glioma inactivated 1
  • dog(477777) leucine-rich, glioma inactivated 1

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-LGI1 (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-LGI1 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Monoclonal Anti-Lgi1 - Fitc antibody produced in mouse, clone S283-7, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry

western blot
Monoclonal Anti-Lgi1 - Atto 594 antibody produced in mouse, clone S283-7, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry

western blot
Monoclonal Anti-Lgi1 - Percp antibody produced in mouse, clone S283-7, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human LGI1,
Species
human
MISSION® esiRNA, targeting mouse Lgi1,
Species
mouse