GPI
glucose-6-phosphate isomerase
Synonyms:
AMF, GNPI, NLK, PGI, PHI, SA-36, SA36
Species:
Human GPI (2821), Rat Gpi (292804), chicken GPI (415783), cow GPI (280808), Horse GPI (100057160), domestic cat GPI (101082360), dog GPI (611942), domestic guinea pig Gpi (100719769), naked mole-rat Gpi (101720720), sheep GPI (101112413)
UniProtKB ID:
Gene ID:
- Human(2821) Summary: This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. [provided by RefSeq, Jul 2008]
- Rat(292804) glucose-6-phosphate isomerase
- chicken(415783) glucose-6-phosphate isomerase
- cow(280808) glucose-6-phosphate isomerase
- Horse(100057160) glucose-6-phosphate isomerase
- domestic cat(101082360) glucose-6-phosphate isomerase
- dog(611942) glucose-6-phosphate isomerase
- domestic guinea pig(100719769) glucose-6-phosphate isomerase
- naked mole-rat(101720720) glucose-6-phosphate isomerase
- sheep(101112413) glucose-6-phosphate isomerase
- Domestic Rabbit(100008744) glucose-6-phosphate isomerase
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