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Merck

FMO1

flavin containing monooxygenase 1

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(2326) Summary: Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. [provided by RefSeq, Jul 2008]
  • Mouse(14261) flavin containing monooxygenase 1
  • Rat(25256) flavin containing monooxygenase 1
  • Thale Cress(838508) flavin-dependent monooxygenase 1
  • cow(508781) flavin containing monooxygenase 1
  • dog(403604) flavin containing monooxygenase 1
  • domestic cat(101087122) flavin containing monooxygenase 1
  • naked mole-rat(101709396) flavin containing monooxygenase 1
  • domestic guinea pig(100723945) flavin containing monooxygenase 1
  • sheep(101105089) flavin containing monooxygenase 1
  • Domestic Rabbit(100009120) flavin containing monooxygenase 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-FMO1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-FMO1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

Proteins

Product Number
Description
Species
Flavin-Containing Monooxygenase-1, Microsomes human, recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human FMO1,
Species
human