CRH
corticotropin releasing hormone
Synonyms:
CRF
Species:
Human CRH (1392), Mouse Crh (12918), Rat Crh (81648), chicken CRH (404297), dog CRH (486977), domestic cat CRH (692345), cow CRH (280755), sheep CRH (101121525), Domestic Rabbit CRH (100301553), domestic guinea pig Crh (100719294)
UniProtKB ID:
Gene ID:
- Human(1392) Summary: Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition. [provided by RefSeq, Apr 2010]
- Mouse(12918) corticotropin releasing hormone
- Rat(81648) corticotropin releasing hormone
- chicken(404297) corticotropin releasing hormone
- dog(486977) corticotropin releasing hormone
- domestic cat(692345) corticotropin releasing hormone
- cow(280755) corticotropin releasing hormone
- sheep(101121525) corticotropin releasing hormone
- Domestic Rabbit(100301553) corticotropin releasing hormone
- domestic guinea pig(100719294) corticotropin releasing hormone
- naked mole-rat(101717831) corticotropin releasing hormone
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Small Molecule - Agonist
Product Number
Description
Species
Small Molecule - Antagonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CRH antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-CRH antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-CRH antibody produced in mouse, clone 2B11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-Corticotropin Releasing Factor antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
bovine, canine, frog, human, mouse, pig, rat, sheep
Application
immunohistochemistry
microarray
radioimmunoassay
microarray
radioimmunoassay
Proteins
Product Number
Description
Species
Corticotropin Releasing Factor, Human and Rat, An immunomodulatory neuropeptide that acts to release ACTH from the anterior pituitary and stimulates the sympathetic nervous system and adrenal medulla.,
Species
human