Cleanup of PCR reactions, restriction digests, sequencing reactions, and agarose and polyacrylamide gel extracts is essential for removing contaminants such as salts, enzymes, unincorporated dNTPs, primers, ethidium bromide, and other impurities that can interfere with downstream analysis. A selection of products for cleaning up DNA and RNA from enzymatic reactions or pre-purified samples is available for flexibility and convenience.
GenElute™-E DNA purification kits use a negative chromatography technique dependent on size exclusion to isolate and purify nucleic acid in a single spin.
Multiscreen® PCR filter plates offer fast, automatable solutions for high-throughput PCR purification, providing high purity and high recovery.
The GenElute™ Gel Extraction Kit is designed for the rapid purification of linear and plasmid DNA fragments from standard or low-melting agarose gels. This kit can also be used to purify DNA from polyacrylamide gels.
The Montage DNA Gel Extraction Kit is a fast, effective solution for fully functional DNA recovery from agarose gel slices. In one 10-minute spin, the agarose gel containing the DNA of interest is fragmented and compressed to extrude the DNA ready for sequencing or cloning.
Montage and MultiScreen® Sequencing Reaction Cleanup products incorporate a patented size-exclusion membrane to yield highly purified sequencing reaction products. Available in 96- and 384-well formats, the plates follow a vacuum-driven protocol, and are automation compatible.