442641

Methapyrilene HCl

analytical standard

• CAS Number: 135-23-9
• EC Number: 205-184-8
• MDL number: MFCD00050665
• UNSPSC Code: 12000000
• PubChem Substance ID: 24867939

Properties

• grade: analytical standard
• Quality Level: 100
• CofA: current certificate can be downloaded
• packaging: ampule of 1000 mg
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): clinical testing
• format: neat
• storage temp.: 2-30°C
• SMILES string: CN(C)CCN(CC1=CC=CS1)C2=NC=CC=C2.Cl
• InChI: 1S/C14H19N3S.ClH/c1-16(2)9-10-17(12-13-6-5-11-18-13)14-7-3-4-8-15-14;/h3-8,11H,9-10,12H2,1-2H3;1H
• InChI key: BONORRGKLJBGRV-UHFFFAOYSA-N
• Gene Information: human ... HRH1(3269)

Description

General description

Methapyrilene is an H₁-receptor antihistamine that is known to cause periportal hepatic necrosis following acute high dose administration to the rat subjects in in vitro studies carried out for the identification of mutagens and/or carcinogens.

Application

Methapyrilene HCl may be used as an analytical reference standard for the determination of the analyte in animal feed, human urine and wastewater by high-performance liquid chromatography (HPLC) and gas chromatography (GC) techniques.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P301 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges