A method for the isolation and culture of embryonic cardiomyocytes from Mexican axolotl.
R W Zajdel et al.
The International journal of developmental biology, 40(4), 907-908 (1996-08-01)
Ylva Rosengardten et al.
Aging cell, 10(6), 1011-1020 (2011-09-10)
Hutchinson-Gilford progeria syndrome (HGPS or progeria) is a very rare genetic disorder with clinical features suggestive of premature aging. Here, we show that induced expression of the most common HGPS mutation (LMNA c.1824C>T, p.G608G) results in a decreased epidermal population...
Simon Joost et al.
Cell reports, 25(3), 585-597 (2018-10-18)
Epithelial tissues, such as the skin, rely on cellular plasticity of stem cells (SCs) from different niches to restore tissue function after injury. How these molecularly and functionally diverse SC populations respond to injury remains elusive. Here, we genetically labeled...
Colleen Nofi et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 66(2), 99-120 (2017-11-09)
This study was aimed to understand the mechanism of persistent cardiac myocyte (CM) survival in myocardial infarction (MI) scars. A transmural MI was induced in 12-month-old Sprague-Dawley rats by permanent coronary artery ligation. The hearts were collected 3 days, 1...
Inma M Berenjeno et al.
Nature communications, 8(1), 1773-1773 (2017-11-25)
Mutations in PIK3CA are very frequent in cancer and lead to sustained PI3K pathway activation. The impact of acute expression of mutant PIK3CA during early stages of malignancy is unknown. Using a mouse model to activate the Pik3ca