R1401

Reversin 205

≥98% (HPLC), film

• Synonym(s): [Boc-Glu(Obzl)]₂-Lys-Ome
• Empirical Formula (Hill Notation): C₄₁H₅₈N₄O₁₂
• CAS Number: 174630-05-8
• Molecular Weight: 798.92
• MDL number: MFCD03788013
• UNSPSC Code: 12161501
• PubChem Substance ID: 329824002
• NACRES: NA.47

Properties

• assay: ≥98% (HPLC)
• form: film
• storage condition: desiccated
• color: colorless
• mp: 101-102 °C
• solubility: DMSO or ethanol: soluble (Insoluble in water)
• storage temp.: −20°C
• SMILES string: COC(=O)[C@H](CCCCNC(=O)[C@H](CCC(=O)OCc1ccccc1)NC(=O)OC(C)(C)C)NC(=O)[C@H](CCC(=O)OCc2ccccc2)NC(=O)OC(C)(C)C
• InChI: 1S/C41H58N4O12/c1-40(2,3)56-38(51)44-30(21-23-33(46)54-26-28-16-10-8-11-17-28)35(48)42-25-15-14-20-32(37(50)53-7)43-36(49)31(45-39(52)57-41(4,5)6)22-24-34(47)55-27-29-18-12-9-13-19-29/h8-13,16-19,30-32H,14-15,20-27H2,1-7H3,(H,42,48)(H,43,49)(H,44,51)(H,45,52)/t30-,31-,32-/m0/s1
• InChI key: BRVAQYBFHAIYLQ-CPCREDONSA-N
• Gene Information: human ... GRIN2B(2904) ; mouse ... GRIN2B(14812) ; rat ... GRIN2B(24410)

Description

General description

Reversin 205 is a hydrophobic peptide.

Application

Reversin 205 has been used to determine the activity of P-glycoprotein in human retinal pigment epithelium.

Biochem/physiol Actions

Peptide chemosensitizer, inhibitor of P-glycoprotein.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)