MilliporeSigma
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P2508

Sigma-Aldrich

Proflavine hemisulfate salt hydrate

powder

Synonym(s):
3,6-Diaminoacridine hemisulfate salt
Empirical Formula (Hill Notation):
C13H11N3 · 0.5 H2SO4 · xH2O
CAS Number:
Molecular Weight:
258.29 (anhydrous basis)
Beilstein:
3921806
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.47

form

powder

Quality Level

solubility

H2O: 10 mg/mL

fluorescence

λex 444 nm; λem 508 nm (0.01M HCl)

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[H]O[H].OS(O)(=O)=O.Nc1ccc2cc3ccc(N)cc3nc2c1.Nc4ccc5cc6ccc(N)cc6nc5c4

InChI

1S/2C13H11N3.H2O4S.H2O/c2*14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10;1-5(2,3)4;/h2*1-7H,14-15H2;(H2,1,2,3,4);1H2

InChI key

DTRLDKDFCPUGCA-UHFFFAOYSA-N

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General description

Proflavine is a small, amphipathic, acridine-derived fluorescent dye.Proflavine hemisulfate is used as a rapid stain for cytological studies of biological specimens. It stains cytoplasmic structures and nuclei. Proflavine has the capability to intercalate double stranded DNA.

Application

Proflavine hemisulfate salt hydrate has been used to stain cells of the 1483 cell line. It has also been used as a calibrating dye in fluorescence resonance energy transfer (FRET) analysis.

Packaging

1, 10, 25 g in glass bottle

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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