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N6875

Sigma-Aldrich

2-Naphthyl acetate

Synonym(s):

β-Naphthyl acetate

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About This Item

Linear Formula:
CH3CO2C10H7
CAS Number:
1523-11-1
Molecular Weight:
186.21
Beilstein/REAXYS Number:
1868291
EC Number:
216-194-7
MDL number:
MFCD00004060
UNSPSC Code:
12352204
PubChem Substance ID:
24897794

form

powder

Quality Level

100

impurities

<0.2% Free naphthol

mp

67-70 °C (lit.)

solubility

ethanol: 50 mg/mL

storage temp.

−20°C

SMILES string

CC(=O)Oc1ccc2ccccc2c1

InChI

1S/C12H10O2/c1-9(13)14-12-7-6-10-4-2-3-5-11(10)8-12/h2-8H,1H3

InChI key

RJNPPEUAJCEUPV-UHFFFAOYSA-N

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Application

2-Naphthyl acetate has been used as a substrate:
  • in substrate sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) to examine the composition of lipases in larvae and adult specimens
  • in the preparation of zymograms to identify proteins with lipase activity
  • to measure non-specific esterase activity and β-esterase enzyme activity

Biochem/physiol Actions

2-Naphthyl acetate/β-naphthyl acetate (BNA) is an ester substrate. It can be used in staining gels to detect esterase activity. BNA dissolved in acetone and ethanol produces a dark and very light/no background respectively. Hence destaining is not necessary if ethanol is used to dissolve BNA for esterase staining of gels.

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H318

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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